DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15255 and nas-23

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001022281.1	Gene:	nas-23 / 3565992	WormBaseID:	WBGene00003542	Length:	537	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	73/243 - (30%)
Similarity:	114/243 - (46%)	Gaps:	40/243 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EGDMMLTEEQQRN-----LEQGAPKA---RNGLINTEKRWPGNVVVYRISDDFDTAHKKAIQTGI 93
            :||:.|:.|...|     |:....|.   ||.:. .:..|..| |.:.:........:.::...:
Worm    86 QGDIHLSFEHLSNIVREQLDHSRTKRTAFRNAMY-PKTIWLPN-VPFELHGSLSAKSRSSLVAAM 148

  Fly    94 DTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAVG---YQGAPQEMNLEIYPLGEGCFRPGTIL 155
            ...|.|||:.|::.|.| |.||.::.:..||::.||   .|||      :|..:|.||...|...
Worm   149 AFWEKHTCVAFKKRTSE-KVYLLMSGQEEGCWSTVGRDEAQGA------QILNIGTGCEMFGITS 206

  Fly   156 HEFMHALGFYHQQSSSIRDDFINVI---------YENIVPGKEFNFQKYADTVVTDFEVGYDYDS 211
            ||..||||.:|:||...||:::.::         |:..|.||: |.:.|...        ||..|
Worm   207 HEIAHALGLFHEQSRYDRDNYVQIVKSRIAQTNFYDFAVVGKK-NMETYGQK--------YDIGS 262

  Fly   212 CLHYRPGAFSINGEDTIVPLDSSA--VIGQRVGLSSKDIDKINIMYKC 257
            .:||||..||::|.::|:..|.:.  .:||..|.|..|:.|||..|.|
Worm   263 VMHYRPTEFSLDGGNSIIAKDVNMQNTMGQFRGPSFIDVAKINRHYNC 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	64/206 (31%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	61/198 (31%)
nas-23	NP_001022281.1	Astacin	122..310	CDD:279708	63/204 (31%)
		ZnMc_astacin_like	128..308	CDD:239807	60/195 (31%)
		CUB	384..454	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910