DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-39

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001360030.1	Gene:	nas-39 / 3565986	WormBaseID:	WBGene00003555	Length:	928	Species:	Caenorhabditis elegans

Alignment Length:	258	Identity:	72/258 - (27%)
Similarity:	120/258 - (46%)	Gaps:	27/258 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IIYVLLLQVVLNSGKPLPAGVYDPEEAGGFV-EGDMMLTEEQQRNLEQGAPKARNGLINTEKRWP 69
            |:.::.|.:|:....|.            |: .||:..    :|........:|......|:.||
Worm    10 IVNIIFLFIVVEFVLPT------------FIRSGDVRF----RRYYRNNGRVSRAATAKKERIWP 58

  Fly    70 GNVVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQG-A 133
            ..::.:.|:.:|...|:......:...|..||:.|.......|.|:|.|....||.:.||.:| .
Worm    59 EGIIPFVIASNFSGEHQHLFLRAMRHWENFTCVSFVPRQPHHKHYITFTVDKCGCCSYVGRRGEG 123

  Fly   134 PQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADT 198
            ||.::     :|:.|.:.|.::||..|.:||:|:.:...||.::::.|::|..|:::||:|....
Worm   124 PQAIS-----IGKNCDKFGIVVHELGHVVGFWHEHTRPDRDMYVDIFYKSIQTGQDYNFEKSKPE 183

  Fly   199 VVTDFEVGYDYDSCLHYRPGAFSING-EDTIVPLDSSAV---IGQRVGLSSKDIDKINIMYKC 257
            .|......||:.|.:||....||... .|||:|..:|..   |||||.||..||.:...:|||
Worm   184 EVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPNSGFRLEIGQRVQLSEGDIRQTKKLYKC 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	62/197 (31%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	57/189 (30%)
nas-39	NP_001360030.1	ZnMc_BMP1_TLD	48..247	CDD:239808	63/204 (31%)
		CUB	268..343	CDD:214483
		CUB	359..474	CDD:238001
		FXa_inhibition	480..515	CDD:373209
		CUB	519..622	CDD:366096
		FXa_inhibition	629..664	CDD:373209
		CUB	669..780	CDD:238001
		CUB	782..898	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810