DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and Astl

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001099974.1	Gene:	Astl / 296129	RGDID:	1562279	Length:	436	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	82/253 - (32%)
Similarity:	127/253 - (50%)	Gaps:	31/253 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LNSGKPLPA---GVYDPE--EAGGFVEGDMMLTEEQQRNLEQGAPKARNGLINTEKRWPGNV--- 72
            ::..|.:||   |:...|  |:...||||::            .|.....|..|..:||..|
  Rat    49 VSQDKDIPAINQGLISEETPESSFLVEGDII------------RPSPFRLLSVTNNKWPKGVDGI 101

  Fly    73 --VVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAPQ 135
              :.:.:|..:|...::.|.......|..||:|| .|....:.::::...: ||::.||..|..|
  Rat   102 VEIPFLLSSKYDEPSRQVIMEAFAEFERFTCIRF-VAYRGQRDFVSILPMA-GCFSGVGRSGGMQ 164

  Fly   136 EMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVV 200
            .::|....|.:|   .|.:|||.||.|||:|:.|.:.||.:|.|.:..|:||.|.||.|..:
  Rat   165 VVSLAPTCLQKG---RGIVLHELMHVLGFWHEHSRADRDRYIRVNWNEILPGFEINFIKSRN--- 223

  Fly   201 TDFEVGYDYDSCLHYRPGAFSINGEDTIVPLDSSAV-IGQRVGLSSKDIDKINIMYKC 257
            ::....|||.|.:||...|||..|:.||:||.:|:| ||||..||:.||.::..:|.|
  Rat   224 SNMLAPYDYSSVMHYGRFAFSWRGQPTIIPLWTSSVHIGQRWNLSTSDITRVCRLYSC 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	69/198 (35%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	65/190 (34%)
Astl	NP_001099974.1	Astacin	92..283	CDD:279708	69/198 (35%)
		ZnMc	99..281	CDD:294052	65/189 (34%)
		ImpA_N	<305..420	CDD:303075
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		otm46226
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920