DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15255 and Tll2

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_036034.1	Gene:	Tll2 / 24087	MGIID:	1346044	Length:	1012	Species:	Mus musculus

Alignment Length:	202	Identity:	75/202 - (37%)
Similarity:	112/202 - (55%)	Gaps:	14/202 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 TEKRWPGNVVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAV 128
            ||:.|||.|:.|.|..:|....:...:..:...|.|||:.|.|.|||: :::..:.::.||.:.|
Mouse   152 TERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTDEE-SFIVFSYRTCGCCSYV 215

  Fly   129 GYQ-GAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNF 192
            |.: |.||.::     :|:.|.:.|.:.||..|.:||:|:.:...||..:.:|.|||.||:|:||
Mouse   216 GRRGGGPQAIS-----IGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNF 275

  Fly   193 QKYADTVVTDFEVGYDYDSCLHYRPGAFSINGE--DTIVP-LDSSAV---IGQRVGLSSKDIDKI 251
            .|.....|:.....||:||.:||....|| .|.  |||:| .|.:.|   |||||.||..||.:.
Mouse   276 LKMEAGEVSSLGETYDFDSIMHYARNTFS-RGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQA 339

  Fly   252 NIMYKCP 258
            ..:||||
Mouse   340 RKLYKCP 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	71/198 (36%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	67/191 (35%)
Tll2	NP_036034.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	83..135
		ZnMc_BMP1_TLD	147..346	CDD:239808	73/200 (37%)
		Astacin	154..347	CDD:279708	73/200 (37%)
		CUB	348..457	CDD:278839
		CUB	461..570	CDD:278839
		FXa_inhibition	581..613	CDD:291342
		CUB	617..726	CDD:278839
		FXa_inhibition	733..768	CDD:291342
		CUB	773..882	CDD:278839
		CUB	886..999	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810