DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-30

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_490795.5	Gene:	nas-30 / 190803	WormBaseID:	WBGene00003548	Length:	741	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	80/239 - (33%)
Similarity:	123/239 - (51%)	Gaps:	23/239 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EGDMMLTEEQQRNLEQGAPKARNG--------LINTEKRWPGNVVVYRISDDFDTAHKKAIQTGI 93
            |.||:||.:|.:.:...|.:|||.        :..:..||. :|:.:|.... |...||.|:.|:
Worm   294 ESDMVLTVKQMKAIVLAAQEARNPHGRKKRKVITGSVYRWK-SVIPFRFKGG-DAKWKKLIREGL 356

  Fly    94 DTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEF 158
            ...|..||:|:.| ....|.|: :..:..|||::||..|..|     :..:|.||...|.:.||.
Worm   357 GLWEKETCVRWSE-NGPGKDYV-IFFRGSGCYSSVGRTGGSQ-----LISIGYGCEDKGIVAHEV 414

  Fly   159 MHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSIN 223
            .|:|||:|:||...|||:|::..:.|:.|.:.||:|.:...:.|..|.||..|.:||...||:.:
Worm   415 GHSLGFWHEQSRPDRDDYIHLRKDWIIKGTDGNFEKRSWEEIEDMGVPYDVGSVMHYGSNAFTKD 479

  Fly   224 GED-TIVPLDS--SAVIGQRVGLSSKDIDKINIMY---KCPILL 261
            .:. ||...||  ...||||..||..|:.::|.:|   .||:.|
Worm   480 WDQITIETKDSRYQGTIGQRQKLSFIDVKQVNRLYCNSVCPVAL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	67/197 (34%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	64/187 (34%)
nas-30	NP_490795.5	ZnMc_astacin_like	336..514	CDD:239807	64/185 (35%)
nas-30	NP_490795.5	CUB	564..648	CDD:412131
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163655
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850