DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-13

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_510549.3	Gene:	nas-13 / 185492	WormBaseID:	WBGene00003532	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	73/201 - (36%)
Similarity:	111/201 - (55%)	Gaps:	6/201 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 RNGLINTEKRWPGNVVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTVTAKSG 122
            ||.:..|..:|....:.|.||..:.:..:..|...|:.....||:.|...:..|..|:.: ....
Worm   109 RNAVRQTYLKWEQARIPYTISSQYSSYSRSKIAEAIEEYRKKTCIDFSPKSAGDLDYIHI-VPDD 172

  Fly   123 GCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPG 187
            |||:.||..|..|.::     ||:||.:.|.|:||.|||:||:|:||.:.||:::.:.:.|:..|
Worm   173 GCYSLVGRIGGKQPVS-----LGDGCIQKGIIIHELMHAVGFFHEQSRADRDEYVKINWSNVEAG 232

  Fly   188 KEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSINGEDTIVPLDSSAVIGQRVGLSSKDIDKIN 252
            .:..|.||:..::......|||.|.:||.|.|||.||:.||.|::.:..||||.|.|..||.|||
Worm   233 LQDQFDKYSLNMIDHLGTKYDYGSVMHYAPTAFSKNGKPTIEPIEKNVEIGQRAGFSENDIYKIN 297

  Fly   253 IMYKCP 258
            ::|.||
Worm   298 MLYNCP 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	68/191 (36%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	66/184 (36%)
nas-13	NP_510549.3	Astacin	118..304	CDD:279708	70/192 (36%)
		ZnMc_astacin_like	122..300	CDD:239807	66/183 (36%)
		ShK	367..404	CDD:279838
		ShK	414..450	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.920