DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-14

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_502533.2	Gene:	nas-14 / 184247	WormBaseID:	WBGene00003533	Length:	503	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	88/256 - (34%)
Similarity:	131/256 - (51%)	Gaps:	23/256 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KPLPAGVYDPEEAGGFVEGDMMLTEEQQRN-----------------LEQGAPKARNGLINTEKR 67
            ||..|.:...:.:..| |||:|...|.:::                 ..:....|.|.:...:|.
Worm    61 KPTDAEIESMQNSLLF-EGDIMGVPEIEKSDILKRLRDDPLLDEDEIFRKPFHSALNLVTYPDKL 124

  Fly    68 WPGNVVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTVTAK-SGGCYTAVGYQ 131
            ||...|.|.:.:......:.||....|..:..||:||...||:|..|:.|... :.||.:.||..
Worm   125 WPEGQVPYMLEEGMTNDQRTAIAQAFDEYKTKTCVRFVPKTDDDFDYIYVKRNVAFGCSSYVGRA 189

  Fly   132 GAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYA 196
            |..|.::||:    :.||..|.|.||.||||||:|:.|.:.||||:::..:||.||...||:||.
Worm   190 GGNQTVSLEV----DKCFSKGIIAHELMHALGFFHEHSRTDRDDFVDINEDNIRPGMMRNFEKYP 250

  Fly   197 DTVVTDFEVGYDYDSCLHYRPGAFSINGEDTIVPLDSSAVIGQRVGLSSKDIDKINIMYKC 257
            ..::....:.|||:|.:||...|||.||:.||:|.|:.|.:|||..||..|..|:|.:|:|
Worm   251 RKIIDSLGMPYDYESVMHYHKLAFSRNGKPTIIPKDNEADVGQRYKLSEMDSKKVNKLYQC 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	77/193 (40%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	72/185 (39%)
nas-14	NP_502533.2	Astacin	123..313	CDD:279708	77/193 (40%)
		ZnMc_astacin_like	128..309	CDD:239807	72/184 (39%)
		ShKT	380..414	CDD:214586
		ShK	468..503	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820