DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-12

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_501871.2	Gene:	nas-12 / 182848	WormBaseID:	WBGene00003531	Length:	384	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	73/236 - (30%)
Similarity:	110/236 - (46%)	Gaps:	25/236 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 VEGDMMLTEEQ---QRNLEQGAPKARNGLI--NTEKRWPGNVVVYRISDDFDTAHKKAIQTGIDT 95
            |.|||:||..|   ..|.:......|...|  ::..||..|:|.|.||..:..|.|:.:.:.:..
Worm    46 VFGDMLLTPAQLIRYENSKDSDLSIRGVSIKGSSMNRWSNNIVPYVISPQYSPAQKQILVSSLRY 110

  Fly    96 LELHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEFMH 160
            .|..:|.:|.|.|.::. ||.:.... |||:.||..|..|.::     |...|.....|.||.||
Worm   111 FERVSCFKFVERTTQND-YLFIVPLD-GCYSYVGKIGGRQTLS-----LAADCIADYIIWHEMMH 168

  Fly   161 ALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSINGE 225
            |:||.|:.....||.||.|.|.|::||:..||.|...:.| ::...||:.|.:||...||   |.
Worm   169 AIGFEHEHQRPDRDSFIRVDYANVIPGQMINFDKLKTSHV-EYPDIYDFKSIMHYDGYAF---GR 229

  Fly   226 ---------DTIVPLDSSAVIGQRVGLSSKDIDKINIMYKC 257
                     .|:.||.....:...:..::.||:|:|.:.:|
Worm   230 VDTARRVRLATMTPLKPGVTLEDNMKFTATDIEKLNRLGQC 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	63/201 (31%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	60/193 (31%)
nas-12	NP_501871.2	Astacin	81..272	CDD:279708	63/201 (31%)
		ZnMc_astacin_like	85..267	CDD:239807	60/192 (31%)
		ShK	286..325	CDD:279838
		ShK	347..384	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920