DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-7

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_495552.2	Gene:	nas-7 / 182368	WormBaseID:	WBGene00003526	Length:	382	Species:	Caenorhabditis elegans

Alignment Length:	237	Identity:	79/237 - (33%)
Similarity:	112/237 - (47%)	Gaps:	20/237 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GVYDPEEAGGFVEGDMMLTEEQQRNLEQGAPKARNGLINTEKRWPGNVVVYRISDDFDTAHKKAI 89
            |.:.|.|.....:.|:.|....:          |||:....|.||...:.|.||..:....:..:
Worm    56 GKHIPVEVVNDFKSDIRLPRRHK----------RNGVSRAAKLWPNARIPYAISPHYSPHERALL 110

  Fly    90 QTGIDTLELHTCLRF--REATDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPG 152
            ...:......||:||  |:..:.|  ||.: .|..||::.||.....|.::|:     .||....
Worm   111 AKAVKQYHEKTCIRFVPRQTGEPD--YLFI-GKVDGCFSEVGRTSGVQVLSLD-----NGCMEYA 167

  Fly   153 TILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRP 217
            ||:||.||.:||||:.....||:||::|::||..|....|.|...:..:.:...|||.|.|||..
Worm   168 TIIHEMMHVVGFYHEHERWDRDNFIDIIWQNIDRGALDQFGKVDLSKTSYYGQPYDYKSILHYDS 232

  Fly   218 GAFSINGEDTIVPLDSSAVIGQRVGLSSKDIDKINIMYKCPI 259
            .|||.||..|::|...||.||.....|..||.|||.||.||:
Worm   233 LAFSKNGFPTMLPKVKSATIGNARDFSDVDISKINRMYNCPV 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	69/193 (36%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	64/186 (34%)
nas-7	NP_495552.2	Astacin	87..274	CDD:279708	70/194 (36%)
		ZnMc_astacin_like	91..270	CDD:239807	64/186 (34%)
		ShK	347..382	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920