DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-6

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001040902.1	Gene:	nas-6 / 181796	WormBaseID:	WBGene00003525	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	273	Identity:	96/273 - (35%)
Similarity:	138/273 - (50%)	Gaps:	34/273 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YVLLLQVVLNS----GKPLP------AGVYDPEE----------AGGFVEGDMMLTEEQQRNLEQ 52
            :||||...|.|    .:|..      || |.||:          :|.| :||:...:.....|.:
Worm     4 HVLLLTYCLVSTVVRSQPSADVFRSFAG-YIPEDHRVTHHEWQNSGKF-QGDIDGVDPNLLKLPE 66

  Fly    53 GAPKARNGLINTEKRWPGNVVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTV 117
            | |...|.|.|.:..|.|.|:.|.:...|.....|.::...|:....||:|| |..:....||.:
Worm    67 G-PVLFNALKNKQLTWEGGVIPYEMDTAFSPNEIKILEKAFDSYRRTTCIRF-EKREGQTDYLNI 129

  Fly   118 TAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYE 182
             .|..|||:.||..|..||::     ||.|||....|:||.||::||:|:.|.:.|||.|.:.::
Worm   130 -VKGYGCYSQVGRTGGKQEIS-----LGRGCFFHEIIVHELMHSVGFWHEHSRADRDDHIKINWD 188

  Fly   183 NIVPGKEFNFQKYADTVVTDFE-VGYDYDSCLHYRPGAFSINGEDTIVPLDS--SAVIGQRVGLS 244
            ||:||.:..|.|.: .|:.|.: ..|||.|.:||...|||.||.:||..:::  :.|||..:.||
Worm   189 NILPGMKSQFDKIS-AVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIETVENGFTQVIGTAMDLS 252

  Fly   245 SKDIDKINIMYKC 257
            ..||.|||.:|.|
Worm   253 PLDIVKINKLYSC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	74/195 (38%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	71/187 (38%)
nas-6	NP_001040902.1	Astacin	80..265	CDD:279708	73/192 (38%)
		ZnMc_astacin_like	83..263	CDD:239807	71/187 (38%)
		ShK	299..334	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020