DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and hch-1

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_510440.1	Gene:	hch-1 / 181564	WormBaseID:	WBGene00001828	Length:	605	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	81/256 - (31%)
Similarity:	123/256 - (48%)	Gaps:	41/256 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PEEAGGFVEGDMMLTEEQQ----RNLEQG-------------APKARNGLIN-TEKRWPGNVVVY 75
            |:|.....||||:||:||.    :|:...             |.:.:..:.: ..:||...|..|
Worm    77 PDEIPYLFEGDMVLTDEQMDLIIKNVRDQYWARKSSTNEFLYAIRGKRSMTSFLSERWSFPVPYY 141

  Fly    76 RISDDFDTA---HKKAIQTGIDTLELHTCLRFR-----EATDEDKAYLTVTAKSGGCYTAVG-YQ 131
                 .||:   :..|:..|:...|..||.||.     .::....|...::  ..|||:.:| ..
Worm   142 -----IDTSSGVNTNAVLAGVAKWEQETCARFTRLNSYSSSSRQNALRFIS--GNGCYSNIGKVS 199

  Fly   132 GAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYA 196
            ..||:::     :|.||...||:.||..|||||||:|:...|||:::::.:||.......|.|.:
Worm   200 RFPQDVS-----IGWGCTSLGTVCHEIGHALGFYHEQARYDRDDYVSILTQNIQDMYLSQFTKQS 259

  Fly   197 DTVVTDFEVGYDYDSCLHYRPGAFSINGEDTIVPLDSS--AVIGQRVGLSSKDIDKINIMY 255
            .:.:.|:.|||||.|.:||...|||..|.:||...|.:  |.|||||..|..|:.:||..|
Worm   260 ASSMVDYGVGYDYGSVMHYDQAAFSSTGGNTIATRDPNFQATIGQRVAPSFADVKRINFAY 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	69/201 (34%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	66/195 (34%)
hch-1	NP_510440.1	Astacin	132..323	CDD:279708	69/201 (34%)
		ZnMc_astacin_like	135..320	CDD:239807	66/196 (34%)
		CUB	386..466	CDD:214483
		TSP1	533..565	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910