DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-10

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001257126.1	Gene:	nas-10 / 181287	WormBaseID:	WBGene00003529	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	77/267 - (28%)
Similarity:	117/267 - (43%)	Gaps:	50/267 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GVYDPEEAGGFVEGDMMLTEEQQRNL-------------EQGAPKARNGLI----NTEKRWPG-N 71
            ||..||:.|.| :.|::|||.|...:             ..|:.||:...|    |..::||. :
Worm   246 GVVAPEDNGVF-DKDLLLTETQANFMLNELGKGGEGAIPMPGSAKAKRASIFFEQNLIQKWPSTS 309

  Fly    72 VVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKA----YLTVTAKSGGCYTAVGYQG 132
            .:.|......|...:..::..|..:|..||:||:......|.    |..|.:.|   :..:.|.|
Worm   310 PIPYTFDSSLDNLDQNDVRGAISEIEQKTCIRFKYFASPPKGNHINYQKVNSPS---FCGLSYIG 371

  Fly   133 APQEMNLEIY---PLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQK 194
            ..:..| .:|   ..|.|   .|..:||.|||||..||.....||..|.|.:.||.|      |:
Worm   372 RVEPAN-PVYLSFQCGNG---RGIAVHETMHALGVNHQHLRMDRDKHIKVDWSNINP------QQ 426

  Fly   195 YADTVVTD------FEVGYDYDSCLHYRPGAFSIN-GEDTIVPLDSS----AVIGQRVGLSSKDI 248
            |...||.|      :.|.|.|||.:||.....::| .:.|::||.:.    .::|||..:|:.|:
Worm   427 YDAFVVADSKLYTTYGVKYAYDSIMHYNAYTGAVNIAKPTMIPLVNQQANIGLLGQRAKMSNADV 491

  Fly   249 DKINIMY 255
            :.:|.||
Worm   492 EILNKMY 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	61/209 (29%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	57/203 (28%)
nas-10	NP_001257126.1	Astacin	303..501	CDD:396122	61/209 (29%)
nas-10	NP_001257126.1	ShK	503..540	CDD:396228
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020