DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15255 and nas-37

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001024413.1	Gene:	nas-37 / 181208	WormBaseID:	WBGene00003553	Length:	765	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	76/231 - (32%)
Similarity:	114/231 - (49%)	Gaps:	26/231 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EGDMMLTEEQQRNL--EQGAPKARNGLINTEKR--WPGNVVVYRISDDFDTAHKKAIQTGIDTLE 97
            |.|::||..|..:|  |..:|::|. ..:.:.|  ||...:.|......:| .::.|::.|..:|
Worm    90 ENDIILTLPQAESLLSESNSPRSRR-QAHPDPRNFWPNLTISYEFYGGEET-WRQLIRSAIRHVE 152

  Fly    98 LHTCLRFRE-ATDED--KAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEFM 159
            .:.|.:|:| ..|.|  :.|     :..||::.||..|..|     :..:|.||...|.:.||.:
Worm   153 QNVCFKFKENGGDRDGLRYY-----RGNGCWSNVGRVGGRQ-----LVSIGYGCDSLGIVSHETL 207

  Fly   160 HALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVG--YDYDSCLHYRPGAFSI 222
            ||||.:|:||...||:||:::.:.|..|.|.||.|  .|......:|  ||..|.:||...:|:.
Worm   208 HALGLWHEQSRDDRDNFISIVADKITRGTEGNFAK--RTAANSDNLGQPYDLGSVMHYGAKSFAY 270

  Fly   223 N-GEDTIVPLD--SSAVIGQRVGLSSKDIDKINIMY 255
            : ..|||...|  ....||||.|||.||...||..|
Worm   271 DWSSDTIKTRDWRYQNTIGQRDGLSFKDAKMINTRY 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	67/200 (34%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	63/192 (33%)
nas-37	NP_001024413.1	Astacin	122..309	CDD:279708	66/198 (33%)
		ZnMc_astacin_like	126..306	CDD:239807	63/192 (33%)
		CUB	370..455	CDD:214483
		TSP1	579..626	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020