DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-32

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_503351.3	Gene:	nas-32 / 178595	WormBaseID:	WBGene00003550	Length:	653	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	81/257 - (31%)
Similarity:	119/257 - (46%)	Gaps:	28/257 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PLPAGVYDPEEAGGFVE----GDMMLTEEQQRNL--EQGAPKAR--NGLINTEKRWPGNVVVYRI 77
            |....:::..|..|..|    ||:.|...|...:  ||.:...|  ..:.|..:.|||.||.|..
Worm   157 PPALDMFEVNERAGLNEYLFQGDINLNNNQIAKISSEQSSKSRRKKRQIDNLAQFWPGKVVYYYF 221

  Fly    78 SDDFDTAHKKAIQTGIDTLELHTCLRFR---EATDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNL 139
            .....|..::.::..|..||.:|||:|.   .||:..|.:..|     |||:..|..|..|.::
Worm   222 DSGLTTTVQQIVRDAITFLESNTCLKFELNSTATNRVKIFSGV-----GCYSDTGMLGGEQTLS- 280

  Fly   140 EIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFE 204
                ||.||...||..||..|.||.:|.|..|.|||::.:...::....:.||.|..:...|:.
Worm   281 ----LGYGCEVTGTAAHEIAHTLGLFHTQMRSDRDDYVTIDLTDVPESSQQNFIKLTEATSTNL- 340

  Fly   205 VGYDYDSCLHYRPGAF-SINGEDTIVPLDSSAV--IGQRVGLSSKDIDKINIMY--KCPILL 261
            |.|:|.|.:||...|| |..|.|:|||.|...|  :|.|: ::..|:..:|..|  .||.:|
Worm   341 VDYEYGSFMHYSGRAFVSSGGVDSIVPKDPVMVYTMGGRI-VTFLDLKMLNTHYSCSCPTIL 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	66/199 (33%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	63/190 (33%)
nas-32	NP_503351.3	Astacin	210..397	CDD:279708	66/198 (33%)
		ZnMc_astacin_like	214..393	CDD:239807	63/190 (33%)
		CUB	464..>528	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920