DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and Mep1a

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_032611.2	Gene:	Mep1a / 17287	MGIID:	96963	Length:	760	Species:	Mus musculus

Alignment Length:	220	Identity:	75/220 - (34%)
Similarity:	119/220 - (54%)	Gaps:	24/220 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 NLEQG---APKARNGLINTEKRW--PGNVVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREAT 108
            ||.||   .|:.||.:.:...||  |   :.|.::|:.:...|.||....:...|.:|:.|:...
Mouse    65 NLFQGDILLPRTRNAMRDPSSRWKLP---IPYILADNLELNAKGAILHAFEMFRLKSCVDFKPYE 126

  Fly   109 DEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIR 173
            .| .:|: :..|..||::.:|.|...|.::     :||||....||.||.:|||||:|:||.:.|
Mouse   127 GE-SSYI-IFQKLSGCWSMIGDQQVGQNIS-----IGEGCDFKATIEHEILHALGFFHEQSRTDR 184

  Fly   174 DDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSINGEDTI------VPLD 232
            ||::|:.::.|:...|.||..|.|..:||....|||:|.:||  |.||.|..::|      :| :
Mouse   185 DDYVNIWWDQIITDYEHNFNTYDDNTITDLNTPYDYESLMHY--GPFSFNKNESIPTITTKIP-E 246

  Fly   233 SSAVIGQRVGLSSKDIDKINIMYKC 257
            .:.:|||....|:.|:.::|.||.|
Mouse   247 FNTIIGQLPDFSAIDLIRLNRMYNC 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	68/200 (34%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	62/190 (33%)
Mep1a	NP_032611.2	ZnMc	46..271	CDD:381785	74/218 (34%)
		MAM	281..444	CDD:366209
		MATH	443..607	CDD:351761
		EGF	688..722	CDD:333761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44135
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910