DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and nas-36

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_492109.2	Gene:	nas-36 / 172506	WormBaseID:	WBGene00003552	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	69/230 - (30%)
Similarity:	105/230 - (45%)	Gaps:	19/230 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EGDMMLTEEQQRNLEQGAPK------ARNGLINTEKRWPGNVVVYRISDDFDTAHKKAIQTGIDT 95
            |||:.|:..|..::.:...|      .|:.:.:....|....:.||..:..|......|...|..
Worm    99 EGDIFLSRRQAVDILKALSKDKTKRLRRSFVSDKTATWKTMPIKYRFHESIDFYTISQIIAAIRF 163

  Fly    96 LELHTCLRFREATDE-DKAYLTVTAKSG-GCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEF 158
            .|..||:.|...:|. |..|:...  || |||:.:|..|..|.::     :||.|.:.|.|.||.
Worm   164 WEDSTCITFENVSDSPDGDYIEFF--SGQGCYSMIGRNGGRQGIS-----IGESCVKMGVIEHEI 221

  Fly   159 MHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSIN 223
            .||||.:|:||......::.:..:.|:|....:|.:..|.:.| ..:.||..|.:||...|||::
Worm   222 GHALGLWHEQSRPDALGYVTIERDFILPSYISDFLQRDDEIDT-LGIPYDLGSVMHYGSTAFSVD 285

  Fly   224 GED-TIVPLDS--SAVIGQRVGLSSKDIDKINIMY 255
            .:. |:|..||  ...||||..||..|:..||..|
Worm   286 QKSKTVVTRDSLYQQTIGQREKLSFYDVATINTAY 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	62/195 (32%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	60/189 (32%)
nas-36	NP_492109.2	Astacin	134..323	CDD:279708	62/195 (32%)
		ZnMc_astacin_like	140..320	CDD:239807	60/187 (32%)
		CUB	380..478	CDD:214483
		TSP1	510..556	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820