DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and astl2d.2

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	XP_031756346.1	Gene:	astl2d.2 / 105947175	XenbaseID:	XB-GENE-22069740	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	295	Identity:	84/295 - (28%)
Similarity:	141/295 - (47%)	Gaps:	54/295 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IYVLLLQVVLNSGKPLPAGVYDPEEAGG-------FVEGD----MMLTEEQQRNL---------- 50
            |.::|:..:|  |:.|.|.:.|.:.:..       |.|.|    |....|:|.:.
Frog     5 ICIILVSCLL--GRVLSAPLQDTDSSDNNNEQNDFFGEDDFYSLMTKANEEQNDFFGEDDFYSLM 67

  Fly    51 -----------EQG---APKARNGLINTEKRWP---GNVVV-YRISDDFDTAHKKAIQTGIDTLE 97
                       .||   ...:|:.::.|:..|.   |.|.| |.:...:.:.....|.:.::...
Frog    68 TKANEGSRVRRVQGDIAVRVSRSTIVCTDCFWQKSNGIVYVPYTLDKQYSSDQINTITSAMEVYS 132

  Fly    98 LHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEG-CFRPGTILHEFMHA 161
            ..||::|...|||:. |:.:|: ..||::.:|.||..|.:::|     :| |...||.:||..||
Frog   133 TLTCVQFVPYTDEED-YIAITS-GDGCWSYMGRQGGAQVVSVE-----KGYCTSEGTTMHELNHA 190

  Fly   162 LGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFS-INGE 225
            |||.|:||.|.||::::::|:.|.||...||:|..   ..:....|||.|.:||...||| ..|:
Frog   191 LGFVHEQSRSDRDNYVDIMYQYISPGDIVNFKKME---TNNLNTTYDYHSIMHYPAWAFSNTTGQ 252

  Fly   226 DTIV-PLDSSAVIGQRVGLSSKDIDKINIMYKCPI 259
            :||| .|:.:..:|....:::.||.|||.:|:|.:
Frog   253 NTIVAKLNPNTPLGPGSTMTNLDITKINRLYQCDV 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	66/198 (33%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	64/188 (34%)
astl2d.2	XP_031756346.1	ZnMc	103..285	CDD:412141	65/191 (34%)
		CUB	288..399	CDD:238001	84/295 (28%)
		CUB	402..513	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010