DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and astl3a.3

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	XP_031746774.1	Gene:	astl3a.3 / 100498584	XenbaseID:	XB-GENE-22069675	Length:	529	Species:	Xenopus tropicalis

Alignment Length:	305	Identity:	101/305 - (33%)
Similarity:	140/305 - (45%)	Gaps:	63/305 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLLLQVVLNSGKPLPAGVYDP----------------EEAGGFVEGDMMLTEEQQRNLE------ 51
            ::||..::.|....||.:..|                |..|...|.|.:.||...|.:|
Frog     9 IILLACIMGSAWTYPAQIIFPYQEMLEKDSLTNLDLLEALGKSAEKDALATEGTVRGMEMPVLGK 73

  Fly    52 -----------------------QG---APKARNGLINTEKRWP----GNVVV-YRISDDFDTAH 85
                                   ||   .||.|:.:..||..||    |.|:| |..|.::....
Frog    74 KSGSVDVFTQISKVNRGIRVPTYQGDILRPKGRSAMNCTECLWPKSTDGTVIVPYNFSSNYSADQ 138

  Fly    86 KKAIQTGIDTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFR 150
            ....::.:...|..||:||....:|.. :|::.: ..||.:.:|..|..|.:.|:.|    ||..
Frog   139 LALFKSTMQEYESLTCVRFVPRANETD-FLSIVS-DNGCASFLGKVGGDQTVQLDSY----GCIY 197

  Fly   151 PGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHY 215
            .|.|.||..|||||||:||.|.|||::.:..|||:||.|.||.| ||:  .:..:.|||.|.:||
Frog   198 RGIIQHELNHALGFYHEQSRSDRDDYVTIHTENIIPGYEGNFNK-ADS--NNLGLEYDYSSVMHY 259

  Fly   216 RPGAFSINGEDTIVPL-DSSAVIGQRVGLSSKDIDKINIMYKCPI 259
            ...|||.||..||||. |.:..||||.|||..|:.|||.:|:|.:
Frog   260 SGDAFSKNGNLTIVPKPDPTVPIGQRDGLSILDVSKINRLYQCDV 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	79/197 (40%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	76/186 (41%)
astl3a.3	XP_031746774.1	ZnMc_hatching_enzyme	121..302	CDD:239810	77/189 (41%)
		CUB	306..414	CDD:238001
		CUB	419..527	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010