DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and astl2d.5

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	XP_031756347.1	Gene:	astl2d.5 / 100495579	XenbaseID:	XB-GENE-22069752	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	73/220 - (33%)
Similarity:	118/220 - (53%)	Gaps:	19/220 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 QRNLEQGAPKARNGLINTEKRWP---GNVVV-YRISDDFDTAHKKAIQTGIDTLELHTCLRFREA 107
            |.::..|.  :|:.:..||..|.   |.|.| |.:.|.:..:....:.:.::.....||::|...
Frog    60 QEDIAVGV--SRSAITYTECLWQKTNGTVYVPYTLDDKYSNSEVNTMTSAMEVYATLTCVQFVPY 122

  Fly   108 TDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEG-CFRPGTILHEFMHALGFYHQQSSS 171
            ||||. |:.:|: ..||::.:|.|...|.:::|     :| |...||.:||..|||||.|:||.|
Frog   123 TDEDD-YVNITS-GDGCWSYMGRQRGAQVVSVE-----KGYCTSEGTTMHELNHALGFVHEQSRS 180

  Fly   172 IRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFS-INGEDTIVPL-DSS 234
            .||:::|::|:.|.||....|:|...   .:....|||.|.:||...||| ..|::|||.. :.:
Frog   181 DRDNYVNIMYQYISPGDVAEFKKMES---NNLGTTYDYRSVMHYPAWAFSNTTGQNTIVAKPNPN 242

  Fly   235 AVIGQRVGLSSKDIDKINIMYKCPI 259
            .:||....::|.||.|||.:|:|.:
Frog   243 IIIGAGNTMTSLDIIKINRLYECDV 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	67/198 (34%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	65/188 (35%)
astl2d.5	XP_031756347.1	ZnMc	83..265	CDD:412141	66/191 (35%)
		CUB	268..377	CDD:395345	73/220 (33%)
		CUB	382..493	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010