DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and astl3c

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	XP_002937470.2	Gene:	astl3c / 100491451	XenbaseID:	XB-GENE-22069695	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	292	Identity:	102/292 - (34%)
Similarity:	137/292 - (46%)	Gaps:	52/292 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IYVLLLQVVLNSGKPLPAGVYDPEEAGGFVEGDMMLTEEQQRNLEQGAP-----------KARNG 60
            |.::||..|:.|....||.|..|..|.|......:|.|.::.......|           :|..|
Frog     5 ISIILLTCVIESVWSFPAQVTMPALADGITASKEILEENKKSGPGNKKPESSVDVFTQIAEANKG 69

  Fly    61 ----------LIN-------TEKRWP----GNVVV-----YRISDDFDTAHKKAIQTGIDTLELH 99
                      |||       ::..||    |.|||     |..|.|..|..|.|:|. .:||
Frog    70 NMALTEGGDILINIGRSATSSDYLWPKSADGTVVVPYIFSYNYSADELTLFKTAMQE-FETL--- 130

  Fly   100 TCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEFMHALGF 164
            ||:||...|.: :.:|.:.: :|||.:.||..|..|::.|..|    ||...|.|.||..|||||
Frog   131 TCVRFVPKTIQ-RDFLNIVS-NGGCLSMVGRNGGGQKVELASY----GCMSRGVIQHELNHALGF 189

  Fly   165 YHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSIN-GEDTI 228
            ||:...|.|||::.:|.|||:|..|..|.|   ....:..:.|||:|.:||....|||: .:.||
Frog   190 YHEHMRSDRDDYVTIITENIIPSYENYFSK---RKTNNMGIIYDYNSVMHYSRNTFSISPDKSTI 251

  Fly   229 VPL-DSSAVIGQRVGLSSKDIDKINIMYKCPI 259
            ||. |.|..||||.|||..||.||..:|:|.:
Frog   252 VPKPDPSIPIGQRDGLSILDILKIKKLYQCDV 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	82/202 (41%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	79/191 (41%)
astl3c	XP_002937470.2	ZnMc	99..281	CDD:381785	80/194 (41%)
		CUB	290..393	CDD:366096
		CUB	398..508	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020