DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and astl3b.4

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	XP_031746772.1	Gene:	astl3b.4 / 100491283	XenbaseID:	XB-GENE-22069691	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	303	Identity:	99/303 - (32%)
Similarity:	140/303 - (46%)	Gaps:	61/303 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLLLQVVLNSGKPLPAGVYDP----------------EEAGGFVEGDMMLTEEQQRNL-----EQ 52
            ::||..::.|....||.:..|                :..|...|.|.:.||...|.:     :.
Frog     9 IILLACIMGSAWTYPAQIIFPYQEKLDKDSLTNLDLLKALGKSAEKDALATEGTVREMPVLGKKS 73

  Fly    53 GA-------------------------PKARNGLINTEKRWP----GNVVV-YRISDDFDTAHKK 87
            |:                         |:.|:.:..||..||    |.|:| |..|.::......
Frog    74 GSVDVFTQISKVNRGISVPTYEGDILRPEGRSAMNCTECLWPKSTDGTVIVPYNFSSNYSADQLA 138

  Fly    88 AIQTGIDTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPG 152
            ..::.:...|..||:||....:| .|:|.:.:.| ||.:.:|..|..|.:.|..|    ||...|
Frog   139 LFKSAMQEYESLTCVRFVPRANE-TAFLNIISGS-GCVSFLGKLGGAQTVQLASY----GCIYRG 197

  Fly   153 TILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRP 217
            .|.||..|||||||:||.|.|||::.:..|||:||.|.||.| |:|  .:..:.|||.|.:||..
Frog   198 IIQHELNHALGFYHEQSRSDRDDYVTIHTENILPGYEGNFNK-ANT--NNLGLEYDYSSVMHYPG 259

  Fly   218 GAFSINGEDTIVPL-DSSAVIGQRVGLSSKDIDKINIMYKCPI 259
            .|||.||..||||. |.:..||||.|||..|:.|||.:|:|.:
Frog   260 DAFSKNGNLTIVPKPDPTVPIGQRDGLSILDVSKINRLYQCDV 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	81/197 (41%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	78/186 (42%)
astl3b.4	XP_031746772.1	ZnMc_hatching_enzyme	119..300	CDD:239810	79/189 (42%)
		CUB	304..412	CDD:238001
		CUB	417..525	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010