DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek3 and Lrg1

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:NP_084072.1 Gene:Lrg1 / 76905 MGIID:1924155 Length:342 Species:Mus musculus


Alignment Length:303 Identity:82/303 - (27%)
Similarity:119/303 - (39%) Gaps:62/303 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 PPLRPRLPLHLHLLLWLLCCCSQLGQLRAE----CPAVCECKWKSGKESVLCLNANLTHIPQPLD 109
            |...|...:||.:..      |.|.||.|.    ||.:.|....|.:...|.... |..:|:   
Mouse    56 PSSLPADTVHLSVEF------SNLTQLPAAALQGCPGLRELHLSSNRLQALSPEL-LAPVPR--- 110

  Fly   110 AGTQLLDLSGNEIQLIPDDSFATAQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLSQNLLSA 174
              .:.|||:.|.::.:|...|:|:  .||..:.|....||.:.....:.|..|..|||::|.||:
Mouse   111 --LRALDLTRNALRSLPPGLFSTS--ANLSTLVLRENQLREVSAQWLQGLDALGHLDLAENQLSS 171

  Fly   175 IPSLAL------------YHVSE------------LRELRLSGNPILRVPDDAFGHVPQLVKLEL 215
            :||..|            |::.|            |:.|.|.||.:.|:.|......|.|..|.|
Mouse   172 LPSGLLASLGALHTLDLGYNLLESLPEGLLRGPRRLQRLHLEGNRLQRLEDSLLAPQPFLRVLFL 236

  Fly   216 SDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLA-----SLHGLELARNTWNCSCSL 275
            :|.:|..:|..:|.||: .|:.|.|..|.||....|....|.     ...|.:::.|.|.|..:|
Mouse   237 NDNQLVGVATGSFQGLQ-HLDMLDLSNNSLSSTPPGLWAFLGRPTRDMQDGFDISHNPWICDKNL 300

  Fly   276 RPLRAW-------MLQQNIPSGIPPTCESPPRLSGRAWDKLDV 311
            ..|..|       |..||     ...|..|..:.|:.  .|||
Mouse   301 ADLCRWLVANRNKMFSQN-----DTRCAGPEAMKGQR--LLDV 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 51/185 (28%)
leucine-rich repeat 112..137 CDD:275380 7/24 (29%)
LRR_8 137..196 CDD:290566 23/82 (28%)
leucine-rich repeat 138..161 CDD:275380 5/22 (23%)
leucine-rich repeat 162..185 CDD:275380 11/34 (32%)
LRR_8 184..245 CDD:290566 22/72 (31%)
leucine-rich repeat 186..209 CDD:275380 7/22 (32%)
leucine-rich repeat 210..234 CDD:275380 9/23 (39%)
leucine-rich repeat 235..258 CDD:275380 8/27 (30%)
LRRCT 267..316 CDD:214507 15/52 (29%)
IG_like 328..428 CDD:214653
Ig 335..425 CDD:143165
Lrg1NP_084072.1 leucine-rich repeat 65..86 CDD:275380 8/26 (31%)
LRR_8 66..121 CDD:290566 17/66 (26%)
LRR_RI <74..294 CDD:238064 62/228 (27%)
leucine-rich repeat 87..110 CDD:275380 4/23 (17%)
LRR_8 109..169 CDD:290566 19/66 (29%)
leucine-rich repeat 111..134 CDD:275380 7/24 (29%)
leucine-rich repeat 135..158 CDD:275380 5/22 (23%)
leucine-rich repeat 159..182 CDD:275380 10/22 (45%)
LRR_8 162..217 CDD:290566 16/54 (30%)
leucine-rich repeat 183..206 CDD:275380 2/22 (9%)
LRR_8 205..265 CDD:290566 21/60 (35%)
leucine-rich repeat 207..230 CDD:275380 7/22 (32%)
leucine-rich repeat 231..254 CDD:275380 9/23 (39%)
leucine-rich repeat 255..278 CDD:275380 8/22 (36%)
LRRCT 292..338 CDD:214507 15/52 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831253
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.