DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek3 and Cpn2

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:NP_082180.2 Gene:Cpn2 / 71756 MGIID:1919006 Length:547 Species:Mus musculus


Alignment Length:379 Identity:97/379 - (25%)
Similarity:141/379 - (37%) Gaps:93/379 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   101 LTHIP----QPLDAGTQLLDLSGNEIQLIPDDSFAT----------------------AQLLNLQ 139
            ||.:|    |.| .|.|:|.||.|.:..:|:.:..:                      :||.:|:
Mouse   181 LTQLPKGAFQSL-TGLQMLKLSNNMLARLPEGALGSLSSLQELFLDGNAITELSPHLFSQLFSLE 244

  Fly   140 KVYL---ARCHLRL-------------IERHAFRKL--------INLVELDLSQNLLSAIPSLAL 180
            .::|   |.|||.:             ::.:|.|.|        ..|:.|.||.|.|..||..|.
Mouse   245 MLWLQHNAICHLPVSLFSSLHNLTFLSLKDNALRTLPEGLFAHNQGLLHLSLSYNQLETIPEGAF 309

  Fly   181 YHVSELRELRLSGNPILRVPDDAFGHVPQLVKLELSDCRLSHIAVRAFAGLESSLEWLKLDGNRL 245
            .::|.|..|.||.|.|..:|:..|.::.|||||.|....|:.:....|..| |.|:.|.|..|:|
Mouse   310 TNLSRLVSLTLSHNAITDLPEHVFRNLEQLVKLSLDSNNLTALHPALFHNL-SRLQLLNLSRNQL 373

  Fly   246 SEVRSGTITSLASLHGLELARNTWNCSCSLRPLRAWM-LQQNIPSGIPPTCESPPRLSGRAWDKL 309
            :.:..|...:...|..|.|..|.|.|.|.|..|.:|: |..|..|.....|..|..|.|:....|
Mouse   374 TTLPGGIFDTNYDLFNLALLGNPWQCDCHLSYLTSWLRLYNNQISNTHTFCAGPAYLKGQLVPNL 438

  Fly   310 DVDDFACVPQIVATDTTAHG-------------VEGRNITMSCYVEGVPQPAV---------KWL 352
            ..:...|..........|.|             ||||.....|.... |:..|         :||
Mouse   439 KQEQLICPVNPGHLSFRALGLDEGEPAGSWDLTVEGRAAHSQCAYSN-PEGTVLLACEESRCRWL 502

  Fly   353 LKNRLIANLSAGGDGDSDSEPRTAAATQ--GRKTYVVNMLRNASNLTILTADMQ 404
                   |:.......|||......::|  |        ||::..|..:|..::
Mouse   503 -------NIQLSSRDGSDSAAMVYNSSQEWG--------LRSSCGLLRVTVSIE 541

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 55/202 (27%)
leucine-rich repeat 112..137 CDD:275380 8/46 (17%)
LRR_8 137..196 CDD:290566 24/82 (29%)
leucine-rich repeat 138..161 CDD:275380 9/46 (20%)
leucine-rich repeat 162..185 CDD:275380 9/22 (41%)
LRR_8 184..245 CDD:290566 23/60 (38%)
leucine-rich repeat 186..209 CDD:275380 8/22 (36%)
leucine-rich repeat 210..234 CDD:275380 8/23 (35%)
leucine-rich repeat 235..258 CDD:275380 6/22 (27%)
LRRCT 267..316 CDD:214507 15/49 (31%)
IG_like 328..428 CDD:214653 20/101 (20%)
Ig 335..425 CDD:143165 15/81 (19%)
Cpn2NP_082180.2 LRRNT 21..52 CDD:214470
LRR_8 73..133 CDD:290566
leucine-rich repeat 75..98 CDD:275380
LRR 1 98..119
leucine-rich repeat 99..122 CDD:275380
LRR_8 121..181 CDD:290566 97/379 (26%)
LRR 2 122..143
leucine-rich repeat 123..146 CDD:275380
LRR 3 146..167
leucine-rich repeat 147..170 CDD:275380
LRR_RI 149..374 CDD:238064 55/194 (28%)
LRR 4 170..191 3/9 (33%)
LRR_8 171..229 CDD:290566 12/48 (25%)
leucine-rich repeat 171..194 CDD:275380 5/13 (38%)
LRR 5 194..215 7/20 (35%)
leucine-rich repeat 195..218 CDD:275380 6/22 (27%)
LRR_8 217..277 CDD:290566 8/59 (14%)
LRR 6 218..239 0/20 (0%)
leucine-rich repeat 219..242 CDD:275380 2/22 (9%)
LRR 7 242..263 6/20 (30%)
leucine-rich repeat 243..266 CDD:275380 6/22 (27%)
LRR_8 266..325 CDD:290566 18/58 (31%)
LRR 8 266..287 3/20 (15%)
leucine-rich repeat 267..290 CDD:275380 3/22 (14%)
LRR 9 290..311 9/20 (45%)
leucine-rich repeat 291..314 CDD:275380 9/22 (41%)
LRR_8 313..373 CDD:290566 23/60 (38%)
LRR 10 314..335 8/20 (40%)
leucine-rich repeat 315..338 CDD:275380 8/22 (36%)
LRR 11 338..359 8/20 (40%)
leucine-rich repeat 339..360 CDD:275380 7/20 (35%)
LRR 12 362..383 6/20 (30%)
leucine-rich repeat 363..382 CDD:275380 6/18 (33%)
LRRCT 395..436 CDD:214507 14/40 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831239
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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