DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek3 and lgi3

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:NP_001034768.1 Gene:lgi3 / 654830 ZFINID:ZDB-GENE-060217-4 Length:551 Species:Danio rerio


Alignment Length:298 Identity:69/298 - (23%)
Similarity:99/298 - (33%) Gaps:113/298 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 RPRLPLHLHLLLWLLC----CC-----SQLGQLRAECPAVCECKWKSGKESVLC----------- 96
            |||..|......|.:|    |.     .:.......|||.|.|.    |:|..|           
Zfish     5 RPRRTLRWPDWRWSVCVLLFCMFGTAPGRKAPKSPRCPATCSCT----KDSAFCVDTKVIPKSFP 65

  Fly    97 --------LNANLTHIPQPLDAGTQLLD---LSGNEIQLIPDDSFATAQLLNLQKVYLARCHLRL 150
                    :||..|.||:...:...||.   |:.|...:|.||:|  :.|.:||.:::....::.
Zfish    66 TGIISLTMVNAAFTEIPEGAFSHMHLLQFLLLNSNTFSVISDDAF--SGLGHLQYLFIENNDIQA 128

  Fly   151 IERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAFGHVPQLVKLEL 215
            :.:|.||.|.:|..|.||.|.|..:|          |||              |.|         
Zfish   129 LSKHTFRGLKSLTHLSLSNNNLQVLP----------REL--------------FKH--------- 160

  Fly   216 SDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWNCSCSLRPLRA 280
                                                    |..|..|:|..|::.|.|.::.|..
Zfish   161 ----------------------------------------LDILTDLDLRGNSFRCDCKIKWLVD 185

  Fly   281 WMLQQNIPSGIPPT-CESPPRLSGRAWDKLDVDDFACV 317
            ||.:.|  :.:||. |.||....||...:|...||.|:
Zfish   186 WMEKTN--TSVPPIYCASPFEFQGRRIHELTPRDFNCI 221

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 31/159 (19%)
leucine-rich repeat 112..137 CDD:275380 9/27 (33%)
LRR_8 137..196 CDD:290566 16/58 (28%)
leucine-rich repeat 138..161 CDD:275380 6/22 (27%)
leucine-rich repeat 162..185 CDD:275380 7/22 (32%)
LRR_8 184..245 CDD:290566 5/60 (8%)
leucine-rich repeat 186..209 CDD:275380 5/22 (23%)
leucine-rich repeat 210..234 CDD:275380 0/23 (0%)
leucine-rich repeat 235..258 CDD:275380 1/22 (5%)
LRRCT 267..316 CDD:214507 17/49 (35%)
IG_like 328..428 CDD:214653
Ig 335..425 CDD:143165
lgi3NP_001034768.1 LRR_8 92..150 CDD:290566 19/59 (32%)
leucine-rich repeat 92..115 CDD:275378 8/24 (33%)
LRR_4 115..>150 CDD:289563 11/34 (32%)
leucine-rich repeat 116..139 CDD:275378 6/22 (27%)
LRR 137..160 CDD:197688 12/46 (26%)
leucine-rich repeat 140..163 CDD:275378 13/95 (14%)
leucine-rich repeat 164..176 CDD:275378 4/11 (36%)
LRRCT 172..220 CDD:214507 17/49 (35%)
EPTP 224..265 CDD:281697
EPTP 271..311 CDD:281697
EPTP 316..362 CDD:281697
EPTP 365..407 CDD:281697
EPTP 412..454 CDD:281697
EPTP 457..498 CDD:281697
EPTP 503..543 CDD:281697
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170574231
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.840

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