DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek3 and lgi1b

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:NP_001122241.1 Gene:lgi1b / 654829 ZFINID:ZDB-GENE-060217-1 Length:543 Species:Danio rerio


Alignment Length:265 Identity:58/265 - (21%)
Similarity:97/265 - (36%) Gaps:73/265 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 LLW----LLCCCSQLGQLRAECPAVCECKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNEI 122
            |||    ||...|:.|: :..||:.|.|.    |::.||.|                       :
Zfish    14 LLWVAAVLLFAESRRGK-QPRCPSGCTCT----KDNALCEN-----------------------V 50

  Fly   123 QLIPDDSFATAQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELR 187
            :.:|                           |:|..  :::.|...::..|.|...:..|...|:
Zfish    51 RSVP---------------------------HSFPP--DVISLSFVKSGFSEIAGGSFLHTPSLQ 86

  Fly   188 ELRLSGNPILRVPDDAFGHVPQLVKLELSDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGT 252
            .|..:.|....:.:|||..:|.|..|.:.:.::..|:..||.||:|.:. |.|..|.|..:....
Zfish    87 LLLFTANSFDLIDEDAFQGLPHLEYLFIENNKIESISPHAFRGLKSLIH-LSLAYNNLETLPRDI 150

  Fly   253 ITSLASLHGLELARNTWNCSCSLRPLRAWMLQQNIPSGIPPT-----CESPPRLSGRAWDKLDVD 312
            ...:.:|..::|..|.::|.|.|:.|..||...|      .|     |..|....|:..:.|...
Zfish   151 FKGMDALTKVDLRGNLFSCDCKLKWLVEWMFSTN------ATVDQLYCSGPSPYQGKKINDLMPQ 209

  Fly   313 DFACV 317
            .|.|:
Zfish   210 SFDCI 214

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 28/156 (18%)
leucine-rich repeat 112..137 CDD:275380 1/24 (4%)
LRR_8 137..196 CDD:290566 9/58 (16%)
leucine-rich repeat 138..161 CDD:275380 2/22 (9%)
leucine-rich repeat 162..185 CDD:275380 4/22 (18%)
LRR_8 184..245 CDD:290566 18/60 (30%)
leucine-rich repeat 186..209 CDD:275380 6/22 (27%)
leucine-rich repeat 210..234 CDD:275380 7/23 (30%)
leucine-rich repeat 235..258 CDD:275380 4/22 (18%)
LRRCT 267..316 CDD:214507 14/53 (26%)
IG_like 328..428 CDD:214653
Ig 335..425 CDD:143165
lgi1bNP_001122241.1 LRR_8 83..143 CDD:290566 18/60 (30%)
LRR_4 83..124 CDD:289563 10/40 (25%)
leucine-rich repeat 85..108 CDD:275378 6/22 (27%)
LRR_4 107..147 CDD:289563 13/40 (33%)
leucine-rich repeat 109..132 CDD:275378 7/22 (32%)
leucine-rich repeat 133..156 CDD:275378 4/23 (17%)
leucine-rich repeat 157..169 CDD:275378 3/11 (27%)
LRRCT 165..213 CDD:214507 14/53 (26%)
EPTP 217..258 CDD:281697
EPTP 263..304 CDD:281697
EPTP 309..355 CDD:281697
EPTP 358..400 CDD:281697
EPTP 405..447 CDD:281697
EPTP 450..491 CDD:281697
EPTP 496..536 CDD:281697
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170574245
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.840

Return to query results.
Submit another query.