| Sequence 1: | NP_001162986.1 | Gene: | kek3 / 34912 | FlyBaseID: | FBgn0028370 | Length: | 1021 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_065913.1 | Gene: | LRFN1 / 57622 | HGNCID: | 29290 | Length: | 771 | Species: | Homo sapiens |
| Alignment Length: | 950 | Identity: | 208/950 - (21%) |
|---|---|---|---|
| Similarity: | 296/950 - (31%) | Gaps: | 309/950 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 40 GPRPQRRLHPPLRPRLPLHLHLLLWLLCCCSQLGQLRAECPAVCECKWKSGKESVLCLNANLTHI 104
Fly 105 PQPLDAGTQLLDLSGNEIQLIPDDSFATAQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLSQ 169
Fly 170 NLLSAIPSLALYHVSELRELRLSGNPILRVPDDAFGHVPQLVK-LELSDCRLSHIAVRAFAGLES 233
Fly 234 SLEWLKLDGNRLSEVRSGTITSLASLHGLELAR-------------------------------- 266
Fly 267 NTWNCSCSLRPLRAWMLQQNIPSGIPPTCESPPRLSGRAWDKLDVDDFACVPQIVATDTTAHG-- 329
Fly 330 VEGRNITMSCYVEGVPQPAVKWLLKN-RLIANLS---AGGDGDSDSEPRTAAATQGRKTYVVNML 390
Fly 391 RNASNLTILTADMQDAGIYTCAAENKAGKVEASVTLAV-----SRRPPEAPWGVRIILLGAVAAL 450
Fly 451 LLVGGSSFAA--------------ICLCSLQRRRKLRLW---NSVPPVRR-----------SESY 487
Fly 488 EKIEMTARTRPDLGGGASCGGGSATGAGLFHDAEEQGYLRAAHTPLNDNDAGQA-----AAIVNP 547
Fly 548 SAGS--AQRRNGDYLHVSTHCDDEEEDQQLHHHPQQQPASQHHPHPNQQQHQQRKGSQGHVVSAS 610
Fly 611 GANNSAPLEETDLHI---PRLIDIGGTDSASSSISSQVDAAARLAGYAGHTWKTTPIATTKINSP 672
Fly 673 HSKPVTSAAPSSLNTQATPYAHYGNHPADEMATSVFCSEGQESDLFDSNYPDLLDIAKYAVAQAQ 737
Fly 738 QEGRGQGYAQATTTPN-------GG----LCTLPRKLKTSGKYFR---NSSDSQSPLLADNSSKY 788
Fly 789 GSSTLGDGSFLNEAMGLGR---RYSAESSYANYSSTATYTGGGQRANSFLNLVQSGAHQGKLLPS 850
Fly 851 HLGQKPSLPSSPVQHQRSLSSAATPLLDFSALASRAAGAA 890 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| kek3 | NP_001162986.1 | LRR_RI | <110..267 | CDD:238064 | 45/189 (24%) |
| leucine-rich repeat | 112..137 | CDD:275380 | 6/24 (25%) | ||
| LRR_8 | 137..196 | CDD:290566 | 17/58 (29%) | ||
| leucine-rich repeat | 138..161 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 162..185 | CDD:275380 | 6/22 (27%) | ||
| LRR_8 | 184..245 | CDD:290566 | 22/61 (36%) | ||
| leucine-rich repeat | 186..209 | CDD:275380 | 10/22 (45%) | ||
| leucine-rich repeat | 210..234 | CDD:275380 | 7/24 (29%) | ||
| leucine-rich repeat | 235..258 | CDD:275380 | 8/22 (36%) | ||
| LRRCT | 267..316 | CDD:214507 | 12/48 (25%) | ||
| IG_like | 328..428 | CDD:214653 | 30/105 (29%) | ||
| Ig | 335..425 | CDD:143165 | 26/93 (28%) | ||
| LRFN1 | NP_065913.1 | LRR_RI | <65..174 | CDD:238064 | 32/110 (29%) |
| LRR_8 | 65..125 | CDD:290566 | 16/61 (26%) | ||
| LRR 1 | 66..87 | 5/22 (23%) | |||
| leucine-rich repeat | 67..90 | CDD:275380 | 6/24 (25%) | ||
| LRR 2 | 90..111 | 5/20 (25%) | |||
| leucine-rich repeat | 91..114 | CDD:275380 | 6/22 (27%) | ||
| LRR_8 | 113..174 | CDD:290566 | 20/60 (33%) | ||
| LRR 3 | 114..135 | 6/20 (30%) | |||
| leucine-rich repeat | 115..138 | CDD:275380 | 6/22 (27%) | ||
| LRR 4 | 138..159 | 10/20 (50%) | |||
| leucine-rich repeat | 139..163 | CDD:275380 | 10/23 (43%) | ||
| LRR_8 | 162..222 | CDD:290566 | 17/60 (28%) | ||
| LRR 5 | 163..184 | 6/21 (29%) | |||
| leucine-rich repeat | 164..187 | CDD:275380 | 7/23 (30%) | ||
| LRR_4 | 165..203 | CDD:289563 | 11/38 (29%) | ||
| LRR 6 | 187..208 | 7/20 (35%) | |||
| leucine-rich repeat | 188..211 | CDD:275380 | 8/22 (36%) | ||
| LRR 7 | 211..232 | 2/20 (10%) | |||
| leucine-rich repeat | 212..230 | CDD:275380 | 2/17 (12%) | ||
| LRRCT | 252..>284 | CDD:214507 | 10/36 (28%) | ||
| IG_like | 310..385 | CDD:214653 | 30/101 (30%) | ||
| Ig | 314..387 | CDD:299845 | 28/99 (28%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 397..422 | 7/35 (20%) | |||
| fn3 | 426..500 | CDD:278470 | 18/107 (17%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 654..743 | 29/135 (21%) | |||
| PDZ-binding | 768..771 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 127 | 1.000 | Inparanoid score | I4688 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 1 | 1.000 | - | - | otm41933 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.960 | |||||