DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek3 and flrt2

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:NP_001093513.1 Gene:flrt2 / 571972 ZFINID:ZDB-GENE-070705-267 Length:662 Species:Danio rerio


Alignment Length:355 Identity:94/355 - (26%)
Similarity:139/355 - (39%) Gaps:109/355 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 LLLWLLCCCSQLGQLR--AECPAVCECKWKSGKESVLCLNANLTHIPQ----------------- 106
            |..||....|...|..  :.||..|.|    .:..|.|...:||.:|.                 
Zfish    16 LRFWLTVLLSLHVQFSPVSSCPEECRC----DRTFVYCNERSLTSVPLGVQEGYKTLFLHNNQIN 76

  Fly   107 ----PLD----AGTQLLDLSGNEIQLIPDDSFATAQLLNLQ--------KVYLARCH----LRL- 150
                ||:    |..:.:.|.||::...|.:.....::|:||        :..||:.|    |.| 
Zfish    77 NAGFPLELHNVASVETVYLYGNQLDEFPLNLPKNVRVLHLQENNIQTISRAALAQLHMLEELHLD 141

  Fly   151 --------IERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAFGHV 207
                    :|..|||:.::|..|.|::|.||:|| :.|  .::|:||||..|.|..:.:|||.:|
Zfish   142 DNSISTVGVEEGAFREALSLKLLFLTKNHLSSIP-IGL--PADLKELRLDENRIADIDEDAFQNV 203

  Fly   208 P------------------------------------------------QLVKLELSDCRLSHIA 224
            .                                                .|.||.|.:.::..|.
Zfish   204 TTLQRLLLDGNLLEDEAIAPGTFQDLVNLKELSLARNSLTAPPPLLPSVSLTKLNLQENQIDTIE 268

  Fly   225 VRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWNCSCSLRPLRAWMLQQNIPS 289
            |.||||| |.||.|.:..|.|..:..|....|.||..|....|.|.|.||::.:.||:  :::||
Zfish   269 VTAFAGL-SKLEKLDISNNLLQILPPGVFDGLRSLRILNARNNLWRCDCSIKWVIAWL--RSLPS 330

  Fly   290 GIPP---TCESPPRLSGRAWDKLDVDDFAC 316
            .|..   ||:||.|:.|....:|.:|...|
Zfish   331 AINVRGFTCQSPERVRGMVIRELTLDAIDC 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 59/225 (26%)
leucine-rich repeat 112..137 CDD:275380 4/24 (17%)
LRR_8 137..196 CDD:290566 26/79 (33%)
leucine-rich repeat 138..161 CDD:275380 11/43 (26%)
leucine-rich repeat 162..185 CDD:275380 9/22 (41%)
LRR_8 184..245 CDD:290566 27/108 (25%)
leucine-rich repeat 186..209 CDD:275380 11/70 (16%)
leucine-rich repeat 210..234 CDD:275380 11/23 (48%)
leucine-rich repeat 235..258 CDD:275380 7/22 (32%)
LRRCT 267..316 CDD:214507 18/51 (35%)
IG_like 328..428 CDD:214653
Ig 335..425 CDD:143165
flrt2NP_001093513.1 LRRNT 36..62 CDD:214470 9/29 (31%)
leucine-rich repeat 45..65 CDD:275378 5/19 (26%)
leucine-rich repeat 66..89 CDD:275378 2/22 (9%)
leucine-rich repeat 90..110 CDD:275380 4/19 (21%)
LRR_8 109..171 CDD:290566 16/61 (26%)
leucine-rich repeat 111..134 CDD:275380 5/22 (23%)
LRR_RI 114..310 CDD:238064 54/199 (27%)
leucine-rich repeat 135..160 CDD:275380 6/24 (25%)
leucine-rich repeat 161..181 CDD:275380 9/22 (41%)
LRR_8 182..242 CDD:290566 11/59 (19%)
leucine-rich repeat 182..205 CDD:275380 11/22 (50%)
leucine-rich repeat 206..231 CDD:275380 0/24 (0%)
leucine-rich repeat 232..253 CDD:275380 0/20 (0%)
LRR_8 253..311 CDD:290566 22/58 (38%)
leucine-rich repeat 254..277 CDD:275380 11/23 (48%)
leucine-rich repeat 278..301 CDD:275380 7/22 (32%)
TPKR_C2 310..361 CDD:301599 19/53 (36%)
fn3 429..503 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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