DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek3 and LRRC52

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:NP_001005214.2 Gene:LRRC52 / 440699 HGNCID:32156 Length:313 Species:Homo sapiens


Alignment Length:254 Identity:65/254 - (25%)
Similarity:106/254 - (41%) Gaps:47/254 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 AECPAVCECKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNEIQLIPDDSFATAQLLNL--Q 139
            ::||..|.|:    .:.|:|....||..|..:...|:.|.|:.|.|..:|      |..|.|  .
Human    24 SKCPNNCLCQ----AQEVICTGKQLTEYPLDIPLNTRRLFLNENRITSLP------AMHLGLLSD 78

  Fly   140 KVYLARC---HLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPD 201
            .||| .|   .:|.:..:.|..:..|:.||||.|.|::|.......:|.|.:|.::.||      
Human    79 LVYL-DCQNNRIREVMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVQLNIANNP------ 136

  Fly   202 DAFGHVPQLVKLELSDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHGLELAR 266
                |:..|.|...::              .:||.:|.|....|..:.|..:..|.:|..|.|:.
Human   137 ----HLLSLHKFTFAN--------------TTSLRYLDLRNTGLQTLDSAALYHLTTLETLFLSG 183

  Fly   267 NTWNCSCSLRPLRAWMLQQNI-PS-GIPPTCESPPRLSGRAWDKLDVDD---FACVPQI 320
            |.|.|:||......:::..:: || .:..||..|..|:|  |....|.:   :.|:..:
Human   184 NPWKCNCSFLDFAIFLIVFHMDPSDDLNATCVEPTELTG--WPITRVGNPLRYMCITHL 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 41/161 (25%)
leucine-rich repeat 112..137 CDD:275380 7/24 (29%)
LRR_8 137..196 CDD:290566 19/63 (30%)
leucine-rich repeat 138..161 CDD:275380 7/27 (26%)
leucine-rich repeat 162..185 CDD:275380 8/22 (36%)
LRR_8 184..245 CDD:290566 12/60 (20%)
leucine-rich repeat 186..209 CDD:275380 5/22 (23%)
leucine-rich repeat 210..234 CDD:275380 2/23 (9%)
leucine-rich repeat 235..258 CDD:275380 6/22 (27%)
LRRCT 267..316 CDD:214507 14/53 (26%)
IG_like 328..428 CDD:214653
Ig 335..425 CDD:143165
LRRC52NP_001005214.2 PRK15387 <2..>93 CDD:185285 23/79 (29%)
LRRNT 26..55 CDD:214470 9/32 (28%)
leucine-rich repeat 35..54 CDD:275380 5/18 (28%)
LRR 1 54..75 8/26 (31%)
leucine-rich repeat 55..78 CDD:275380 9/28 (32%)
LRR 2 78..99 6/21 (29%)
LRR_8 79..136 CDD:338972 17/57 (30%)
leucine-rich repeat 79..102 CDD:275380 6/23 (26%)
LRR 3 102..123 8/20 (40%)
leucine-rich repeat 103..126 CDD:275380 8/22 (36%)
LRR_8 126..185 CDD:338972 17/82 (21%)
LRR 4 126..148 7/31 (23%)
leucine-rich repeat 127..151 CDD:275380 7/47 (15%)
LRR 5 151..172 6/20 (30%)
leucine-rich repeat 152..175 CDD:275380 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141314
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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