DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kek3 and tpbga

DIOPT Version :9

Sequence 1:	NP_001162986.1	Gene:	kek3 / 34912	FlyBaseID:	FBgn0028370	Length:	1021	Species:	Drosophila melanogaster
Sequence 2:	NP_919373.2	Gene:	tpbga / 373095	ZFINID:	ZDB-GENE-030827-4	Length:	372	Species:	Danio rerio

Alignment Length:	317	Identity:	84/317 - (26%)
Similarity:	133/317 - (41%)	Gaps:	62/317 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LLLWLLCCCS-QLGQLRAECPAVCECKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNEIQL 124
            ::|.|||..: ..|.|  .||..|||  .....:|.|::.:|..||..:...|:.|.::||.|..
Zfish     9 VVLGLLCAAAVSAGAL--VCPTGCEC--SEAALTVKCVSKDLRDIPSGIPGYTRNLFITGNHISQ 69

  Fly   125 IPDDSFATAQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIP------------- 176
            |..:||  ..|.|:..:.|:...:..::.|.|..|.:|..||||.|.|:.|.
Zfish    70 IGPESF--QGLENVTNLSLSNNRISEVKSHTFSSLRSLRSLDLSNNQLAVIHPEAFTVQSRMLRE 132

  Fly   177 ---SLALYH---------------VSELRELRLSGNPILRVPDDAFGHVPQLVKLELSDCRLSHI 223
               |.|||:               :|:|..|.||.|.::.:|...|.|:..|.:|:|.:..:..|
Zfish   133 LNLSRALYNHSSVMDLATSLRWSSLSDLLVLDLSSNGLVFLPSGIFCHLVGLRRLQLGNNSIVSI 197

  Fly   224 AVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHG--LELARNTWNCSCSLRPLRAWMLQQN 286
            ....|.||: .|:.|.|..|.|..:|...:..|..||.  |.||.|.:.|:|.:.|..||
Zfish   198 HNGTFTGLD-HLQELDLTHNALRTLREEALKELEQLHSARLHLADNPFTCTCDIEPFAAW----- 256

  Fly   287 IPSGIPPTCESPPRLSGRAWDKLDVDDFACVPQIVATDTTAHGVEGRNITMSCYVEG 343
                          |:|.....:|::...|...:...:|:...|  .::.:.|:..|
Zfish   257 --------------LNGSRGQVVDIEGLTCAFPVALHNTSLLTV--GDLELGCHKAG 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kek3	NP_001162986.1	LRR_RI	<110..267	CDD:238064	54/189 (29%)
		leucine-rich repeat	112..137	CDD:275380	9/24 (38%)
		LRR_8	137..196	CDD:290566	23/89 (26%)
		leucine-rich repeat	138..161	CDD:275380	4/22 (18%)
		leucine-rich repeat	162..185	CDD:275380	12/53 (23%)
		LRR_8	184..245	CDD:290566	20/60 (33%)
		leucine-rich repeat	186..209	CDD:275380	8/22 (36%)
		leucine-rich repeat	210..234	CDD:275380	7/23 (30%)
		leucine-rich repeat	235..258	CDD:275380	7/22 (32%)
		LRRCT	267..316	CDD:214507	9/48 (19%)
		IG_like	328..428	CDD:214653	3/16 (19%)
		Ig	335..425	CDD:143165	2/9 (22%)
tpbga	NP_919373.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910