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Protein Alignment kek3 and Lrig3

DIOPT Version :9

Sequence 1:	NP_001162986.1	Gene:	kek3 / 34912	FlyBaseID:	FBgn0028370	Length:	1021	Species:	Drosophila melanogaster
Sequence 2:	NP_796126.4	Gene:	Lrig3 / 320398	MGIID:	2443955	Length:	1117	Species:	Mus musculus

Alignment Length:	988	Identity:	210/988 - (21%)
Similarity:	314/988 - (31%)	Gaps:	289/988 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 WKSGKESVLCL-NANLTHIPQPLDAGTQL---LDLSGNEIQLIPDDSFATAQLLNLQKVYLARCH 147
            |......||.| :.|||.|.:....|..:   |.||.|.|..|..|::...|  .|.::.|...|
Mouse   260 WGLSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQ--KLSELDLTFNH 322

  Fly   148 LRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDD---AFGHVPQ 209
            |..::..:|..|..|..|.:..|.:|.|...|...::.|:.|.|..|.|....:|   ||..:.:
Mouse   323 LSRLDDSSFLGLSLLNALHIGNNKVSYIADCAFRGLTSLKTLDLRNNEISWTIEDMSGAFSGLDR 387

  Fly   210 LVKLELSDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWNCSCS 274
            |.:|.|...|:..|..:|||||: :||.|.|.||.:..::|...:.:..|..|.|..::..|.|.
Mouse   388 LRQLILQGNRIRSITKKAFAGLD-TLEHLDLSGNAIMSLQSNAFSQMKKLQQLHLNTSSLLCDCQ 451

  Fly   275 LRPLRAWMLQQNIPSGIPPTCESPPRLSGRAWDKLDVDDFAC----VPQIVATDTTAHGVEGRNI 335
            ||.|..|:.:.|..|.:..:|..|..|.||:...:..|.|.|    .|||.....|...::|.::
Mouse   452 LRWLPQWVAENNFQSFVNASCAHPQLLKGRSIFTVSPDGFVCDDFPKPQITVQPETQSAIKGSDV 516

  Fly   336 TMSCYVEGVPQPAV--KWLLKNRLI--------ANLSAGG---------------DGDSDSEPRT 375
            :.:|.........:  .|...|..:        |:|.|.|               :..|:.:.:.
Mouse   517 SFTCSAASSSDSPMTFAWKKDNEALQDAEMENYAHLRAQGGELMEYTTILRLRNVEFTSEGKYQC 581

  Fly   376 AAATQGRKTY------VVNML----RNASNLTILTADM--------------------------- 403
            ..:.....:|      .:|||    :...:|||....|
Mouse   582 VISNHFGSSYSVKAKLTINMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPA 646

  Fly   404 ----------------------QDAGIYTCAAENKAGKVEASVTLAVSRRPP-EAPWGVRIILLG 445
                                  :|.|:|:|.|:|.||.|.|:.||.|...|. ..|...|.:..|
Mouse   647 ARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSVSANATLTVLETPSFLRPLLDRTVTKG 711

  Fly   446 AVAALLLVGGSSFAAICLCSLQRRRKLRLWNSVPPVRRSESYEKIEMTARTRPDLGGG------- 503
            ..|.|..:.|.|                     ||.|.:.:.:...:....|.....|
Mouse   712 ETAVLQCIAGGS---------------------PPPRLNWTKDDSPLVVTERHFFAAGNQLLIIV 755

  Fly   504 ---------ASCGGGSATGAGLFHDAEEQGYLRAAHTPLNDNDA-----------GQAA------ 542
                     .:|...:..|.       |:|.:|.:..|....|:           |.|.
Mouse   756 DSDVSDAGKYTCEMSNTLGT-------ERGNVRLSVIPTPTCDSPHMTAPSLDGDGWATVGVVII 813

  Fly   543 AIVNPSAGSA----------QRRNGDYLHVSTHCDDEEEDQQLHHHPQQQP---ASQHHPHPNQQ 594
            |:|....|::          :|||.|       |.....|:.  :.|...|   :||......|.
Mouse   814 AVVCCVVGTSLVWVVIIYHTRRRNED-------CSITNTDET--NLPADIPSYLSSQGTLADRQD 869

  Fly   595 QH-QQRKGSQGHVVSASGANNSAPLEETDLHIPRLIDIGGTDSASSSISSQVDAAARLAGYAGHT 658
            .: ....||....|::||.....|..          |..||.....|..:.|:||
Mouse   870 GYISSESGSHHQFVTSSGGGFFLPQH----------DGAGTCHFDDSSEADVEAA---------- 914

  Fly   659 WKTTPIATTKINSPHSKP-VTSAAPSSLNTQATPYAHYGNHPADEMATSVFCSEGQESDLFDSNY 722
                       :.|...| |.|..|..|....     |...|.:.....  ||....:.|.|...
Mouse   915 -----------SDPFLCPFVGSTGPVYLQGNL-----YSPDPFEVYLPG--CSSDPRTALMDHCE 961

  Fly   723 PDLLDIAKYAVAQAQQEGRGQGYAQATTTP-NGGLCTLP----RKLKTSGKYFRNSSDSQSPLLA 782
            ...:...:::.|:..:|            | ...|.::|    ||| |...|..|...:...|..
Mouse   962 SSYVKQDRFSCARPSEE------------PCERSLKSIPWPHSRKL-TDSTYPPNEGHTVQTLCL 1013

  Fly   783 DNSSKYGSSTLGDGSFLNEAMGLGRRYSAESSYANYSSTATYTGGGQRANSFLNLVQSGAHQGKL 847
            :.||                             .:: ||....|....:|||:     |.....|
Mouse  1014 NKSS-----------------------------VDF-STGPEPGSATSSNSFM-----GTFGKPL 1043

  Fly   848 LPSHL------GQKPSLPSSPVQHQRSLSSAATPLLDFSALASRAAGAANTSVAAYDYHAAQLER 906
            ...||      .|.|.....|. |.:||||   |.||..   |.......|.... :.|....::
Mouse  1044 RRPHLDAFSSSAQPPDCQPRPC-HGKSLSS---PELDSE---SEENDKERTDFRE-ENHRCTYQQ 1100

  Fly   907 FLEEYRNLQDQLC 919
            ....||....|.|
Mouse  1101 IFHTYRTPDCQPC 1113

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.