DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek3 and Lrrc26

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:NP_001014075.1 Gene:Lrrc26 / 311803 RGDID:1308398 Length:334 Species:Rattus norvegicus


Alignment Length:299 Identity:85/299 - (28%)
Similarity:111/299 - (37%) Gaps:69/299 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 RLPLHLHLLLWLLCCCS--------QLG------QLRAECPAVCECKWKSGKESVLCLNANLTHI 104
            |||..|.|||.||...|        .:|      .:...||..|.|. ..||.:  |....|..:
  Rat     8 RLPPQLSLLLLLLLLLSWRRVWTQEHIGTDPSKSPVAPVCPEACSCS-PGGKAN--CSALALPAV 69

  Fly   105 PQPLDAGTQLLDLSGNEIQLIPDDSFATAQLLNLQKVYLA--RCHLRLIERHAFRKLINLVELDL 167
            |..|....:.|.|..|.:..:|..:||.|..|    :||.  ...||.:...||..|..|..|||
  Rat    70 PAGLSWQVRSLLLDRNRVSTLPPGAFADAGAL----LYLVLRENRLRSVHARAFWGLGVLQRLDL 130

  Fly   168 SQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAFGHVPQLVKLELSDCRLSHIAVRAFAGLE 232
            |.|.|..:.......:..|..|.|:||.:..:.....|.:|.|..|.|.|               
  Rat   131 SSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQD--------------- 180

  Fly   233 SSLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWNCSCSLRPLRAWMLQQNIPSGIPPT--C 295
                      |.||.:.:|.:.||.:|..|.|..|.|.|||:||||..|:.:...|:....|  |
  Rat   181 ----------NSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLC 235

  Fly   296 ESPPRLSGRAWDKLD----VDDF------ACVPQIVATD 324
            .||         ||.    :.||      .|...:.|.|
  Rat   236 VSP---------KLQTLNLLTDFPDNAFKQCTQSLAARD 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 42/158 (27%)
leucine-rich repeat 112..137 CDD:275380 7/24 (29%)
LRR_8 137..196 CDD:290566 19/60 (32%)
leucine-rich repeat 138..161 CDD:275380 7/24 (29%)
leucine-rich repeat 162..185 CDD:275380 7/22 (32%)
LRR_8 184..245 CDD:290566 12/60 (20%)
leucine-rich repeat 186..209 CDD:275380 6/22 (27%)
leucine-rich repeat 210..234 CDD:275380 4/23 (17%)
leucine-rich repeat 235..258 CDD:275380 6/22 (27%)
LRRCT 267..316 CDD:214507 19/60 (32%)
IG_like 328..428 CDD:214653
Ig 335..425 CDD:143165
Lrrc26NP_001014075.1 LRR_8 76..135 CDD:290566 21/62 (34%)
LRR 1 76..97 5/20 (25%)
leucine-rich repeat 77..100 CDD:275380 7/22 (32%)
LRR 2 100..121 7/24 (29%)
leucine-rich repeat 101..124 CDD:275380 8/26 (31%)
LRR 3 124..145 7/20 (35%)
LRR_8 125..183 CDD:290566 19/82 (23%)
LRR_4 125..164 CDD:289563 12/38 (32%)
leucine-rich repeat 125..148 CDD:275380 7/22 (32%)
LRR 4 148..169 5/20 (25%)
leucine-rich repeat 149..172 CDD:275380 6/22 (27%)
LRR 5 172..194 8/46 (17%)
leucine-rich repeat 173..196 CDD:275380 10/47 (21%)
leucine-rich repeat 197..239 CDD:275380 18/50 (36%)
TPKR_C2 205..258 CDD:301599 19/61 (31%)
leucine-rich repeat 240..259 CDD:275380 4/18 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 312..334
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166334980
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.930

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