Protein Alignment kek3 and Elfn1

DIOPT Version :9

• Sequence 1: NP_001162986.1
• Gene: kek3 / 34912
• FlyBaseID: FBgn0028370
• Length: 1021
• Species: Drosophila melanogaster
• Sequence 2: NP_001099383.1
• Gene: Elfn1 / 288512
• RGDID: 1308787
• Length: 829
• Species: Rattus norvegicus
• Alignment Length: 1020
• Identity: 181/1020 - (17%)
• Similarity: 288/1020 - (28%)
• Gaps: 426/1020 - (41%)

  Fly   104 IPQPLDAGTQLLDLSGNEIQLIPDDSFATAQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLS 168
            |||.::  ..::||..||.::......:.::..||..:.|.:..:..||..||....||..|.|.
  Rat    54 IPQQIN--NTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLG 116

  Fly   169 QNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAFGHVPQLVKLELSDCRLSHIAVRAFAGLES 233
            .|.|..:....|..:|:|..|.|..|.|..|...||...|.:|.::||
  Rat   117 YNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLS----------------- 164

  Fly   234 SLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWNCSCSLRPLRAWML--------------- 283
                    .||:.::.|||...|..|...|:..|.:.|||.|.....|:.
  Rat   165 --------MNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCE 221

  Fly   284 ------------------QQNIPSGIPPTCE---------SPPR-LSGRAW-------DKLDVDD 313
                              |::|.|.:...|.         .||| :.||:.       ...:..|
  Rat   222 SPPVYAGYFLLGQGRHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPPEPSD 286

  Fly   314 FAC-----------VPQIVATDTTAHGVEGRNITMSCYVEGVPQPAVKWLLKN--RLIANLSAGG 365
            ..|           .|.:|.|            |:....|..|...||.|.:|  .::..|
  Rat   287 MPCADDECFSGDGTTPLVVLT------------TLVPQTEARPSMKVKQLTQNSATIMVQL---- 335

  Fly   366 DGDSDSEPRTAAATQGRKTYVVNMLRNASNLTI--LTADMQD---AGIYT------CAAENKAGK 419
                        .:...:.|.:....|:.:.|:  ||...::   ..:||      |.....:|.
  Rat   336 ------------PSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGT 388

  Fly   420 VEASVTLAVS-RRPPEAPWGVR---------IILLGAVAALLLVGGSSFAAICLCSLQRRRKLRL 474
            ......|.:. .:||..|..|.         :.:||.:..::||.|    |:..| |::||
  Rat   389 HHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLG----AVYYC-LRKRR---- 444

  Fly   475 WNSVPPVRRSESYEK-------------IEMTARTRPDLGGGASCGGGSATGAGLFHDAEEQGYL 526
                   |:.|.::|             ||:......:..|.|....|...|        .:...
  Rat   445 -------RQEEKHKKAVAAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLG--------PEAVT 494

  Fly   527 RAAHTPLNDNDAGQAAAIVNPSAGSAQRRNGDYLHVSTHCDDEEEDQQLHHHPQQQPASQHHPHP 591
            |..:.|...:|..|...:  .|..:.:...|:|:.|.|
  Rat   495 RIPYLPAATSDVEQYKLV--ESGETPKATKGNYIEVRT--------------------------- 530

  Fly   592 NQQQHQQRKGSQGHVVSASGANNSAPLEETDLHIPRLIDIGGTDSASSSISSQVDAAARLAGYAG 656
                        |......|...|.|..||...:..:          |:|:.:||
  Rat   531 ------------GEPPERRGCELSRPAPETQSSVAEI----------STIAKEVD---------- 563

  Fly   657 HTWKTTPIATTKINSPHSKPVTSAAPSSLNTQATPYAHYGNHPADEMATSVFCSEGQESDLFDSN 721
                       ::|.     :.:....:|.:::|.:                  :|.:|.
  Rat   564 -----------RVNQ-----IINNCIDALKSESTSF------------------QGAKSG----- 589

  Fly   722 YPDLLDIAKYAVAQAQQEGRGQGYAQATTTPNGGLCTLPRKLKTSGKYFRNSSDSQSPLLADNSS 786
                      ||:.|:.:                |..|...|.:...:.       ||:..|
  Rat   590 ----------AVSAAEPQ----------------LVLLSEPLASKHSFL-------SPVYKD--- 618

  Fly   787 KYGSSTLGDGSFLNEAMGLGRRYSAESSYANYSSTATYTGGGQRANSFLNLVQSGAHQGKLLPSH 851
                 ..|.|       ||.|.:|.|:: ......:|.:.|..|:........:|||:.....:.
  Rat   619 -----AFGHG-------GLQRHHSVEAA-TGPPRASTSSSGSARSPRTFRAETAGAHKAPATETK 670

  Fly   852 LGQKPSLPSSPVQHQRSLSSAATPLLDFSALASRAAGAANTSVAAYDYHAAQLERFLEEYRNLQD 916
            ..:|    ||||
  Rat   671 YIEK----SSPV----------------------------------------------------- 678

  Fly   917 QLCKMKETCDTIRKKETPLRVAIGQSAAQLADPVMYSAASHSPKPPATSNLKTKTLLPGQPPDPP 981
                 .||..|:....|.|| |....:.|..:.......||..:|||             ||.||
  Rat   679 -----PETILTVTPAATVLR-AEADKSRQYGEHRHSYPGSHPAEPPA-------------PPPPP 724

  Fly   982 PYWLHRNAMLKRLNGDGSAGTNGSGGSPAS-------PQPRQDIF 1019
            |  .|                .|.||..||       |:||..::
  Rat   725 P--TH----------------EGLGGRKASILEPLTRPRPRDLVY 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek3	NP_001162986.1	LRR_RI	<110..267	CDD:238064	39/156 (25%)
		leucine-rich repeat	112..137	CDD:275380	4/24 (17%)
		LRR_8	137..196	CDD:290566	19/58 (33%)
		leucine-rich repeat	138..161	CDD:275380	6/22 (27%)
		leucine-rich repeat	162..185	CDD:275380	6/22 (27%)
		LRR_8	184..245	CDD:290566	14/60 (23%)
		leucine-rich repeat	186..209	CDD:275380	8/22 (36%)
		leucine-rich repeat	210..234	CDD:275380	3/23 (13%)
		leucine-rich repeat	235..258	CDD:275380	6/22 (27%)
		LRRCT	267..316	CDD:214507	16/98 (16%)
		IG_like	328..428	CDD:214653	18/112 (16%)
		Ig	335..425	CDD:143165	17/102 (17%)
Elfn1	NP_001099383.1	LRR	<44..>186	CDD:227223	41/158 (26%)
		leucine-rich repeat	65..85	CDD:275378	3/19 (16%)
		LRR_8	85..144	CDD:404697	19/58 (33%)
		leucine-rich repeat	86..109	CDD:275378	6/22 (27%)
		leucine-rich repeat	110..133	CDD:275378	6/22 (27%)
		leucine-rich repeat	134..157	CDD:275378	8/22 (36%)
		leucine-rich repeat	158..171	CDD:275378	5/37 (14%)
		LRRCT	190..>228	CDD:214507	6/37 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930