Protein Alignment kek3 and Lgi4

DIOPT Version :9

• Sequence 1: NP_001162986.1
• Gene: kek3 / 34912
• FlyBaseID: FBgn0028370
• Length: 1021
• Species: Drosophila melanogaster
• Sequence 2: NP_653139.2
• Gene: Lgi4 / 243914
• MGIID: 2180197
• Length: 537
• Species: Mus musculus
• Alignment Length: 241
• Identity: 60/241 - (24%)
• Similarity: 90/241 - (37%)
• Gaps: 58/241 - (24%)

  Fly    76 RAECPAVCECKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNEIQLIPDDSFATAQLLNLQK 140
            :.:||..|.|    .||:.||..:     |:                  :| :||:|. ||:|.
Mouse    24 KGKCPPHCSC----SKENTLCEGS-----PE------------------LP-ESFSTT-LLSLS- 58

  Fly   141 VYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAFG 205
              |.|..:..::..:|.|:                |||.|        |..:.|....:..|||.
Mouse    59 --LVRMGVSRLKAGSFLKM----------------PSLHL--------LLFTSNTFSVIEGDAFI 97

  Fly   206 HVPQLVKLELSDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWN 270
            .:..|..|.:.|.::..|:..|..||. ||..|.|..|.|..:.......|.:|..::|..|.:.
Mouse    98 GLSYLQYLFIEDNKIGSISKNALRGLR-SLTHLSLANNHLEALPRFLFRGLETLTHVDLRGNPFQ 161

  Fly   271 CSCSLRPLRAWMLQQNIPSGIPPTCESPPRLSGRAWDKLDVDDFAC 316
            |.|.:..|..||...|...| ...|..||.::....:.||...|.|
Mouse   162 CDCRVLWLLQWMPTVNASVG-TGACAGPPAVAQIQLNHLDPKKFKC 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek3	NP_001162986.1	LRR_RI	<110..267	CDD:238064	36/156 (23%)
		leucine-rich repeat	112..137	CDD:275380	5/24 (21%)
		LRR_8	137..196	CDD:290566	11/58 (19%)
		leucine-rich repeat	138..161	CDD:275380	5/22 (23%)
		leucine-rich repeat	162..185	CDD:275380	4/22 (18%)
		LRR_8	184..245	CDD:290566	17/60 (28%)
		leucine-rich repeat	186..209	CDD:275380	5/22 (23%)
		leucine-rich repeat	210..234	CDD:275380	7/23 (30%)
		leucine-rich repeat	235..258	CDD:275380	6/22 (27%)
		LRRCT	267..316	CDD:214507	14/48 (29%)
		IG_like	328..428	CDD:214653
		Ig	335..425	CDD:143165
Lgi4	NP_653139.2	LRR 1	53..74		6/24 (25%)
		leucine-rich repeat	54..77	CDD:275378	7/41 (17%)
		LRR_8	76..136	CDD:290566	21/68 (31%)
		LRR 2	77..98		8/28 (29%)
		leucine-rich repeat	78..101	CDD:275378	7/30 (23%)
		LRR 3	101..122		5/20 (25%)
		LRR_4	102..140	CDD:289563	13/38 (34%)
		leucine-rich repeat	102..125	CDD:275378	7/23 (30%)
		LRR 4	125..146		6/20 (30%)
		leucine-rich repeat	126..149	CDD:275378	6/22 (27%)
		leucine-rich repeat	150..162	CDD:275378	3/11 (27%)
		LRRCT	158..206	CDD:214507	14/48 (29%)
		EAR 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	210..252
		EPTP	<220..251	CDD:281697
		EAR 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	256..298
		EAR 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	302..349
		EAR 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	351..394
		EPTP	351..392	CDD:281697
		EAR 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	396..439
		EPTP	396..438	CDD:281697
		EAR 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	441..483
		EAR 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	487..532

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831274
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840