Protein Alignment kek3 and iglr-1

DIOPT Version :10

• Sequence 1: NP_523575.1
• Gene: kek3 / 34912
• FlyBaseID: FBgn0028370
• Length: 1021
• Species: Drosophila melanogaster
• Sequence 2: NP_510491.2
• Gene: iglr-1 / 184720
• WormBaseID: WBGene00008977
• Length: 695
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 116/547 - (21%)
• Similarity: 183/547 - (33%)
• Gaps: 168/547 - (30%)

  Fly    98 NANLTHIPQPLDAGTQL--LDLSGNEIQLIPDDSFATAQLLNLQKVYLARCHLRLIERHAFRKLI 160
            |.:|...|:.|.|.|.|  ||||.|.::.:..||.   .:.::|:|.|....::.|..|.||.:.
 Worm   113 NCSLKTFPKALMALTSLLELDLSDNMLENLGADSI---HIRSIQRVILRNNQIKSIGVHVFRYMP 174

  Fly   161 NLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAFGHVPQLVKLELSDCRLSHIAV 225
            .|..||||.|.::.:.:........||||.|..|.|..:..|....:.||..|:||...||.:.:
 Worm   175 TLKMLDLSGNNMTRLVTSDFTSAVSLRELILRENKIELIETDTTEPMQQLETLDLSGNLLSEVRL 239

  Fly   226 RA---FAGLES-------------------SLEWLKLDGNRLSEVRSGTITSLASLHGLELARNT 268
            .|   |..|.|                   .|:.|:||...:|.|.:|...||..||.:::..|
 Worm   240 EAQQNFRHLFSLNLSCNPLQIIREGFLQLPDLQVLQLDNCNISVVEAGAFVSLPRLHSMDIKDN- 303

  Fly   269 WNCSCSLRPLRAW-----------MLQQNIPSG----IPPT------------------CESPPR 300
                    |..|:           ..:.||.:.    ||.|                  |.|...
 Worm   304 --------PNLAYFSPYAFSNNTAFYRMNIQNSGFKRIPLTILEKISQLYIKGTQLDCSCTSRDM 360

  Fly   301 LSGRAWDKLDVDDFACVPQIVATDTTAH----------------GVE-----GRNITMSCYVEGV 344
            ....|...:|.:|..|..:|.|....:|                |:.     |.:..:.|..:|.
 Worm   361 QDYGAITIVDWNDATCKTKIGAVQKLSHLEKTGEPCRDNLLTPFGIRQTATVGHSYRIYCANDGT 425

  Fly   345 PQPAVKWLLKNRLIANLSAGGDGDSDSEPRTAAATQGRKTYVVNML------RNASNLTILTADM 403
             ...:.|:..|:  ..:.|       |.|:...::..|..|....|      ||......::.:.
 Worm   426 -NSKLLWISPNK--TTIEA-------SHPKLRKSSDKRTDYFTTTLLDPSFSRNHEERIHISNEY 480

  Fly   404 --------QDAGIYTCAAENKAGKVEASVTLA------------VSRRPPEAPWGVRIILLGAV- 447
                    .|||.|.|.:::....:...:.|.            |:.......|. |.:.:.||
 Worm   481 YGFDVVLENDAGHYECVSKSDMKTITRKIELEVVKPNIYLNASHVATTSVHLNWN-RNLKIEAVD 544

  Fly   448 -AALLLVGGSSFAAICLCSLQRRRKLRLWNSVPPVRRSESYEKIEMTARTRPDLGGGASCGGGSA 511
             .||.:...|.      ...:|:.:|.|:|..      .||..:.::|
 Worm   545 RVALRITASSE------KMFKRQVQLSLYNMF------RSYNLVNLSA----------------- 580

  Fly   512 TGAGLFHDAEEQGYLRAAHTPLNDNDA 538
                      ::.||......|.||||
 Worm   581 ----------DKEYLICLEWYLTDNDA 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek3	NP_523575.1	LRR	<98..>267	CDD:443914	57/192 (30%)
		leucine-rich repeat	112..137	CDD:275380	9/26 (35%)
		leucine-rich repeat	138..161	CDD:275380	7/22 (32%)
		leucine-rich repeat	162..185	CDD:275380	6/22 (27%)
		leucine-rich repeat	186..209	CDD:275380	8/22 (36%)
		leucine-rich repeat	210..234	CDD:275380	10/45 (22%)
		leucine-rich repeat	235..258	CDD:275380	9/22 (41%)
		LRRCT	267..316	CDD:214507	13/81 (16%)
		Ig	331..428	CDD:472250	19/127 (15%)
		Ig strand B	335..339	CDD:409562	0/3 (0%)
		Ig strand C	348..352	CDD:409562	0/3 (0%)
		Ig strand E	394..398	CDD:409562	0/3 (0%)
		Ig strand F	408..413	CDD:409562	2/4 (50%)
		Ig strand G	421..424	CDD:409562	0/2 (0%)
iglr-1	NP_510491.2	LRR	<102..346	CDD:443914	65/244 (27%)
		leucine-rich repeat	106..128	CDD:275380	5/14 (36%)
		leucine-rich repeat	129..151	CDD:275380	8/24 (33%)
		leucine-rich repeat	152..175	CDD:275380	7/22 (32%)
		leucine-rich repeat	176..199	CDD:275380	6/22 (27%)
		leucine-rich repeat	200..223	CDD:275380	8/22 (36%)
		leucine-rich repeat	224..247	CDD:275380	8/22 (36%)
		leucine-rich repeat	248..270	CDD:275380	2/21 (10%)
		leucine-rich repeat	271..294	CDD:275380	9/22 (41%)
		leucine-rich repeat	295..316	CDD:275380	5/29 (17%)
		leucine-rich repeat	320..343	CDD:275380	5/22 (23%)