DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kek3 and fgf23.2

DIOPT Version :9

Sequence 1:	NP_001162986.1	Gene:	kek3 / 34912	FlyBaseID:	FBgn0028370	Length:	1021	Species:	Drosophila melanogaster
Sequence 2:	XP_002940351.1	Gene:	fgf23.2 / 100496800	XenbaseID:	XB-GENE-482986	Length:	254	Species:	Xenopus tropicalis

Alignment Length:	106	Identity:	26/106 - (24%)
Similarity:	42/106 - (39%)	Gaps:	18/106 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 LDLSGNEI---QLIPDDS-FATAQLLNLQKVYLARCHLRLIE----RHAFRKLINLVELDLSQNL 171
            :|.|||..   ....||. |....|.|...||.:..|..:|.    :|.||..::|.......:|
Frog    98 MDKSGNIFGYHDFNHDDCVFKHETLENNFDVYHSPKHNFVISLKEPKHHFRLGMDLPPYSQFLSL 162

  Fly   172 LSAIPSLALYHVSELRELRLSGNPILRVPDDAFGHVPQLVK 212
            .:.|| :..::..|         |.:|:|:..|.....::|
Frog   163 ENEIP-ITRFNAPE---------PEMRIPEGNFADPSDIIK 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kek3	NP_001162986.1	LRR_RI	<110..267	CDD:238064	26/106 (25%)
		leucine-rich repeat	112..137	CDD:275380	8/25 (32%)
		LRR_8	137..196	CDD:290566	13/62 (21%)
		leucine-rich repeat	138..161	CDD:275380	7/26 (27%)
		leucine-rich repeat	162..185	CDD:275380	4/22 (18%)
		LRR_8	184..245	CDD:290566	6/29 (21%)
		leucine-rich repeat	186..209	CDD:275380	4/22 (18%)
		leucine-rich repeat	210..234	CDD:275380	1/3 (33%)
		leucine-rich repeat	235..258	CDD:275380
		LRRCT	267..316	CDD:214507
		IG_like	328..428	CDD:214653
		Ig	335..425	CDD:143165
fgf23.2	XP_002940351.1	FGF	43..160	CDD:238015	17/61 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165161410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930