DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek3 and mxra5

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:XP_002941051.4 Gene:mxra5 / 100495231 XenbaseID:XB-GENE-923372 Length:2851 Species:Xenopus tropicalis


Alignment Length:1303 Identity:222/1303 - (17%)
Similarity:384/1303 - (29%) Gaps:530/1303 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 LHLHLLLWLLCCCSQLGQLRAECPAVCECKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNE 121
            :||.|:|.::..   :.|....||..|.|...|   .|.|...:|..:|..:....:.::|..|.
 Frog    25 IHLWLILAVIIF---VPQNALSCPHPCACYVNS---EVHCTFRSLAAVPSRIPKHVERINLGFNS 83

  Fly   122 IQLIPDDSFATAQLLNLQKVYLARCH---LRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHV 183
            ||.|.:||||     .|.|:.|...|   :|.:...|||.|::|....:|.|.|..|.|..|:.:
 Frog    84 IQSIGEDSFA-----GLSKLELLLIHSNDVRNVPNGAFRDLVSLQVFKMSYNKLKTITSHTLHGL 143

  Fly   184 SELRELRLSGNPILRVPDDAFGHVPQLVKLELSDCRLSHIAVRAFAGL-------ESSLEWLKLD 241
            ..|..|.:..|.|..:..:||..:..|..|.|....|..:....|...       :|:|:.|.|.
 Frog   144 LGLTRLHIDHNQIEFIHPNAFNGLMSLRLLHLEGNLLQQLHANTFCTFNFLGYFRQSTLKHLYLS 208

  Fly   242 GNRLSEVRSGTITSLASLHGLELARNTWNCSCSLRPLRAWMLQ----------QNIPSG-IPPTC 295
            .|.:..:.:..|.::..|..|.|..|.|.|.|:::.|..|..|          ::..:| :.|||
 Frog   209 ENMIQSLPADMIKTMPLLENLYLHGNPWVCDCNIKWLLDWTEQTDGILKCKKDRSYENGQLCPTC 273

  Fly   296 ESPPRLSGR-------------------------------------------------------- 304
            .||..|..|                                                        
 Frog   274 SSPKHLQNREIQSLKDAYCSRPVIYSALRDNSSYAYTEEENGNDPPAAESYHNLLGKVILNMTDE 338

  Fly   305 --------------------AW-----DKLDVD-----DFAC----------------------- 316
                                .|     :::|::     ||.|                       
 Frog   339 HGNKVNLDCDMIKPADFSKITWNQHHPEEIDINATFSLDFECPMNRENYEKLWKLIAYYSEVPVK 403

  Fly   317 ------------------------------VPQIVATD--------------------------- 324
                                          |..::::|                           
 Frog   404 LERELQFNDSPKMTYRYRQNVDHDSYYYTGVKALISSDPSWIMQTTVNIQLNRKMSTAKKVTLSF 468

  Fly   325 ------------------------------TTAHGVEGRNITMSCYVEGVPQPAVKWLLKNRLIA 359
                                          |:...|:|....::|:|:....|:::|.|.:..|.
 Frog   469 STQFAESIHTKEIQYTQNNWVLIEKNEKVKTSCTAVKGTLCQLNCHVKSSEIPSIEWSLPDGTIL 533

  Fly   360 -----------NLSAGGD----------------------------------------------- 366
                       ::|..|.                                               
 Frog   534 KAPYNSPESRFSVSPSGQLVIKEADFPDSGLYYCIARVKHEVDMQLFRVTVQSSSSDVAENHIHV 598

  Fly   367 ----------------GDSDSE-----PRTA---AATQGRKTYVVNMLRNASNLTILTADMQDAG 407
                            |:.|::     |...   |:......|::|   |.| |.|:.|.:.|:|
 Frog   599 LTRNVGDPIALACNVVGNPDADVNWILPNNKIIDASVNNTGLYLLN---NGS-LAIINAKLSDSG 659

  Fly   408 IYTCAAENKAGKVEASVTLAVSRRPPEAPWGVRIILLGAVAALLLV-----------GGSSFAAI 461
            :|.|...|:.|....||.:.::|:..|.|:  :||......:..:.           |||.... 
 Frog   660 LYRCIGINQHGTDHYSVQVEINRKVSEKPY--QIIKTKKQPSFEVPTKPKYNVIDDDGGSGEKD- 721

  Fly   462 CLCSLQRRRKLRLWNSVPPVRR---SESYEKIEMTARTR----PDLGGGASCGGGSATGAGLFHD 519
               :.:...|..:.|...||::   :.:..:::...:.|    |..|...|.|...|.|...|  
 Frog   722 ---TQEESGKYNVKNGARPVKKIGSASTKVRVKQNRKDRRKMKPWKGTERSKGSNIAEGRRKF-- 781

  Fly   520 AEEQGYLRAAHTPLNDNDAGQAAAIVNPSAGSAQRRNGDYLHVSTHCDDEEEDQQLHHHPQQQPA 584
             |.:..:...:..:   |..|.|.|:....|...:|..:: .::|..   .....|.|.| ..|:
 Frog   782 -ESRRRINMGNKQI---DPQQWANILAKVRGKNLQRTTEF-PLATQA---TPTSALRHKP-TPPS 837

  Fly   585 SQHHPHPNQQQHQQRKGSQGHVVSASGANNSAP-LEETDLHIPRLIDIGGTDSASSSISSQVDAA 648
            |...|.|                    |..|.| :|||......|:.|..:.:.:..||   |..
 Frog   838 SIAMPPP--------------------AKESEPYVEETSADEEELLHITSSPTIAQGIS---DVT 879

  Fly   649 ARLAGYAGHTWKTTPIATTKINSPHSKPVTSAAPSSLNTQATPYAHYGNHPADEMATSVFCSEGQ 713
            .                     ||:.:.||..:..:.|...|           .::.|..|..  
 Frog   880 V---------------------SPNDRIVTVISEETDNDSET-----------VLSESKTCKT-- 910

  Fly   714 ESDLFDSNYP--DLLDIAKYAVAQAQQEGRGQGYAQAT---------------TTPNGGLCTLPR 761
                 :|:.|  ||..|         :....:|:..:|               :.|...:.|:..
 Frog   911 -----ESSTPNTDLTTI---------ENSEAEGFTYSTNEDENVILEGNEIHSSAPTTYIQTIEN 961

  Fly   762 KL----KTSGKYFRNSSDSQSPLLADNSSK--YGSSTLGDGSFLNEAMGLGRRYSAESSYANYSS 820
            :.    .|:..|....|:.::...::|:|:  ..|||:       |.:.:|.....|.|.|:..:
 Frog   962 EYIVDSVTTDSYVEEQSNEKTVFESENNSEADLESSTM-------EMLSVGTDDVKELSTASGIT 1019

  Fly   821 TATYTGGGQRANSFLNLVQSGAHQGKLLPSHLGQKPSLP-------------------------- 859
            .|....|.:::.:.           |...::..::||.|                          
 Frog  1020 VAPLLPGVEKSTTI-----------KSSDTYFPEEPSQPPNAESDDSLTTENFILWKEDNDILPT 1073

  Fly   860 ------SSPVQHQRSLSSAATP-----------LLDFSALASRAAGAANTSVAAYDYHAAQLERF 907
                  |:||   .|:|:|.:|           |:....|......:|..:|...:|        
 Frog  1074 INREIQSTPV---TSISNAISPTPSDDQLNIYALVPTQTLIPITTQSAGENVIEVNY-------- 1127

  Fly   908 LEEYRNLQDQLCKMKETCDTI-RKKETPLRVAIGQSAAQLADPVMYSAASHSPKPPATSNLKTKT 971
            .|:|..          ..||| .|..:...::.|......|:|.  :..:.:.||...|.||| |
 Frog  1128 TEDYAG----------NTDTIFPKMSSKSSISRGHKNNYKAEPT--TVTTSTGKPKTDSRLKT-T 1179

  Fly   972 LLP 974
            ::|
 Frog  1180 MIP 1182

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 45/166 (27%)
leucine-rich repeat 112..137 CDD:275380 9/24 (38%)
LRR_8 137..196 CDD:290566 19/61 (31%)
leucine-rich repeat 138..161 CDD:275380 9/25 (36%)
leucine-rich repeat 162..185 CDD:275380 7/22 (32%)
LRR_8 184..245 CDD:290566 16/67 (24%)
leucine-rich repeat 186..209 CDD:275380 6/22 (27%)
leucine-rich repeat 210..234 CDD:275380 5/30 (17%)
leucine-rich repeat 235..258 CDD:275380 5/22 (23%)
LRRCT 267..316 CDD:214507 19/145 (13%)
IG_like 328..428 CDD:214653 29/181 (16%)
Ig 335..425 CDD:143165 26/171 (15%)
mxra5XP_002941051.4 LRRNT 44..75 CDD:214470 9/33 (27%)
leucine-rich repeat 55..72 CDD:275380 4/16 (25%)
leucine-rich repeat 74..97 CDD:275380 10/27 (37%)
PPP1R42 82..238 CDD:411060 46/160 (29%)
LRR_8 96..156 CDD:404697 18/59 (31%)
leucine-rich repeat 98..121 CDD:275380 7/22 (32%)
leucine-rich repeat 122..145 CDD:275380 7/22 (32%)
leucine-rich repeat 146..169 CDD:275380 6/22 (27%)
leucine-rich repeat 170..201 CDD:275380 5/30 (17%)
leucine-rich repeat 202..225 CDD:275380 5/22 (23%)
LRRCT 234..293 CDD:214507 15/58 (26%)
IG 511..584 CDD:214652 8/72 (11%)
IG 598..680 CDD:214652 19/85 (22%)
Herpes_BLLF1 <1269..1567 CDD:282904
Ig 1895..1959 CDD:409353
Ig strand B 1895..1899 CDD:409353
Ig strand C 1908..1912 CDD:409353
Ig strand E 1935..1939 CDD:409353
Ig strand F 1949..1954 CDD:409353
Ig 1989..2066 CDD:416386
Ig strand B 1991..1999 CDD:409353
Ig strand C 2005..2010 CDD:409353
Ig strand C' 2013..2015 CDD:409353
Ig strand D 2025..2029 CDD:409353
Ig strand E 2032..2036 CDD:409353
Ig strand F 2046..2053 CDD:409353
Ig strand G 2056..2066 CDD:409353
Ig 2072..2163 CDD:416386
Ig strand A 2072..2075 CDD:409353
Ig strand A' 2080..2083 CDD:409353
Ig strand B 2089..2096 CDD:409353
Ig strand C 2102..2108 CDD:409353
Ig strand C' 2110..2112 CDD:409353
Ig strand D 2122..2126 CDD:409353
Ig strand E 2129..2134 CDD:409353
Ig strand F 2142..2150 CDD:409353
Ig strand G 2153..2163 CDD:409353
Ig 2172..2252 CDD:416386
Ig strand A 2172..2175 CDD:409353
Ig strand A' 2179..2182 CDD:409353
Ig strand B 2188..2195 CDD:409353
Ig strand C 2201..2210 CDD:409353
Ig strand C' 2212..2214 CDD:409353
Ig strand D 2221..2225 CDD:409353
Ig strand E 2228..2233 CDD:409353
Ig strand F 2241..2249 CDD:409353
Ig 2279..2365 CDD:416386
Ig strand B 2284..2292 CDD:409353
Ig strand C 2298..2303 CDD:409353
Ig strand C' 2306..2308 CDD:409353
Ig strand D 2324..2328 CDD:409353
Ig strand E 2331..2335 CDD:409353
Ig strand F 2345..2352 CDD:409353
Ig strand G 2355..2365 CDD:409353
Ig strand A 2369..2372 CDD:409353
Ig strand A' 2377..2381 CDD:409353
I-set 2382..2459 CDD:400151
Ig strand B 2387..2396 CDD:409353
Ig strand C 2401..2406 CDD:409353
Ig strand C' 2409..2411 CDD:409353
Ig strand D 2419..2422 CDD:409353
Ig strand E 2425..2432 CDD:409353
Ig strand F 2438..2446 CDD:409353
Ig strand G 2449..2459 CDD:409353
Ig 2475..2559 CDD:416386
Ig strand A' 2476..2479 CDD:409353
Ig strand B 2485..2493 CDD:409353
Ig strand C 2499..2504 CDD:409353
Ig strand C' 2507..2509 CDD:409353
Ig strand D 2518..2522 CDD:409353
Ig strand E 2525..2529 CDD:409353
Ig strand F 2539..2546 CDD:409353
Ig strand G 2549..2559 CDD:409353
Ig_3 2565..2643 CDD:404760
Ig strand A' 2574..2577 CDD:409353
Ig strand B 2583..2590 CDD:409353
Ig strand C 2596..2608 CDD:409353
Ig strand C' 2611..2613 CDD:409353
Ig strand D 2617..2620 CDD:409353
Ig strand E 2622..2626 CDD:409353
Ig strand F 2635..2643 CDD:409353
Ig_3 2659..2737 CDD:404760
Ig strand B 2678..2682 CDD:409353
Ig strand C 2691..2695 CDD:409353
Ig strand E 2717..2721 CDD:409353
Ig strand F 2731..2736 CDD:409353
Ig_3 2755..2837 CDD:404760
Ig strand A 2755..2759 CDD:409353
Ig strand A' 2764..2768 CDD:409353
Ig strand B 2772..2781 CDD:409353
Ig strand C 2787..2796 CDD:409353
Ig strand C' 2802..2805 CDD:409353
Ig strand E 2816..2822 CDD:409353
Ig strand F 2829..2837 CDD:409353
Ig strand G 2842..2850 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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