DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek3 and lrfn2

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:XP_031758515.1 Gene:lrfn2 / 100491687 XenbaseID:XB-GENE-6035533 Length:765 Species:Xenopus tropicalis


Alignment Length:431 Identity:108/431 - (25%)
Similarity:156/431 - (36%) Gaps:118/431 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 LLCCCSQLGQ--LRAECPAVCECKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNEIQLIPD 127
            :||.....|.  :...||..|.|:..|.....||....|..:|..:|..|..|.|.||       
 Frog     4 ILCSLLVFGMAVMVNSCPKYCVCQNLSESLGTLCPTKGLLFVPMDIDRRTVELRLGGN------- 61

  Fly   128 DSFATAQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLS 192
                               .:..|.|..|..:..||:|.||:|.:|.|...:...:..||.|.|.
 Frog    62 -------------------FIISINRQDFANMTGLVDLTLSRNTISYIQPYSFIDLESLRSLHLD 107

  Fly   193 GNPILRVPDDAFGHVPQLVKLELSDCRLSHIAVRAFAGLESSLE-------------W------- 237
            .|.:..:.||.|..:..|..|.:::.:|:.||..||..|..:||             |       
 Frog   108 SNRLTNLGDDVFRGLINLQHLIMNNNQLNSIAEDAFEDLLQTLEDLDLSYNNLKTVPWDAVRRMV 172

  Fly   238 ----LKLDGNRLSEVRSGTITSLASLHGLEL--------------AR------------------ 266
                |.||.|.:..:..||...|..|..|:|              ||                  
 Frog   173 NLHQLSLDHNLIYYITEGTFQDLNKLARLDLTSNRLQKLPPDPIFARSQISMTSATPFSPPLSLS 237

  Fly   267 ---NTWNCSCSLRPLRAWMLQQNIPSGIPPTCESPPRLSGRAWDKLDVDDFACVPQIVATDTTAH 328
               |..:|:|.|..||....:.::     .||.||..|.||.:..:..::|.|.|.::...|...
 Frog   238 FGGNPLHCNCELLWLRRLDREDDM-----ETCASPSALKGRYFWYVREEEFVCEPPLITQYTQRL 297

  Fly   329 GV-EGRNITMSCYVEGVPQPAVKWLLKN-RLIANLSAGGDGDSDSEPRTAAATQGRKTYVVNMLR 391
            .| ||:..::.|...|.|.|.:.|:..: |||.|.|           ||.....|          
 Frog   298 LVLEGQTASLKCKAVGDPLPVIHWVAPDGRLIGNSS-----------RTTVYDNG---------- 341

  Fly   392 NASNLTILTADMQDAGIYTCAAENKAGKVEASVTLAVSRRP 432
               .|.||....:|.|.:||.|.|.||::.|.|.|::.:.|
 Frog   342 ---TLDILITTSKDYGTFTCIAANAAGELTAPVELSIVQIP 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 47/215 (22%)
leucine-rich repeat 112..137 CDD:275380 5/24 (21%)
LRR_8 137..196 CDD:290566 16/58 (28%)
leucine-rich repeat 138..161 CDD:275380 3/22 (14%)
leucine-rich repeat 162..185 CDD:275380 8/22 (36%)
LRR_8 184..245 CDD:290566 23/84 (27%)
leucine-rich repeat 186..209 CDD:275380 8/22 (36%)
leucine-rich repeat 210..234 CDD:275380 8/23 (35%)
leucine-rich repeat 235..258 CDD:275380 10/46 (22%)
LRRCT 267..316 CDD:214507 14/48 (29%)
IG_like 328..428 CDD:214653 30/101 (30%)
Ig 335..425 CDD:143165 25/90 (28%)
lrfn2XP_031758515.1 LRR_8 51..111 CDD:404697 21/85 (25%)
leucine-rich repeat 53..76 CDD:275380 8/48 (17%)
leucine-rich repeat 77..100 CDD:275380 8/22 (36%)
LRR_8 100..160 CDD:404697 18/59 (31%)
leucine-rich repeat 101..124 CDD:275380 8/22 (36%)
leucine-rich repeat 125..148 CDD:275380 8/22 (36%)
LRR_8 148..208 CDD:404697 13/59 (22%)
leucine-rich repeat 150..173 CDD:275380 3/22 (14%)
leucine-rich repeat 174..197 CDD:275380 7/22 (32%)
LRRCT 241..285 CDD:214507 14/48 (29%)
Ig 288..375 CDD:416386 31/110 (28%)
Ig strand A 288..291 CDD:409353 0/2 (0%)
Ig strand A' 295..298 CDD:409353 0/2 (0%)
Ig strand B 304..312 CDD:409353 1/7 (14%)
Ig strand C 318..323 CDD:409353 1/4 (25%)
Ig strand C' 326..328 CDD:409353 0/1 (0%)
Ig strand D 334..338 CDD:409353 2/3 (67%)
Ig strand E 341..345 CDD:409353 2/16 (13%)
Ig strand F 355..362 CDD:409353 3/6 (50%)
Ig strand G 365..375 CDD:409353 4/9 (44%)
fn3 417..485 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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