DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek3 and tlr13

DIOPT Version :9

Sequence 1:NP_001162986.1 Gene:kek3 / 34912 FlyBaseID:FBgn0028370 Length:1021 Species:Drosophila melanogaster
Sequence 2:XP_002935047.2 Gene:tlr13 / 100485164 XenbaseID:XB-GENE-5873547 Length:948 Species:Xenopus tropicalis


Alignment Length:199 Identity:56/199 - (28%)
Similarity:98/199 - (49%) Gaps:12/199 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 ECPAVCECKWKS-GKESVLCLNANLTHIP---QPLDAGTQLLDLSGNEIQLIPDDSFATAQLLNL 138
            ||....:|..:. ..|...|:..::..:.   |.|...|::|::|.|||..|  |.:..:.|..|
 Frog    24 ECYGYRKCSLEGIHTEYANCVGQSVVTLADAIQDLPYQTRVLNISENEISKI--DGYTFSHLPKL 86

  Fly   139 QKVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDA 203
            |::.|.:..:..::..||..|.:|:.||||.||:.::.::.|..:..|:...||.|.|..:....
 Frog    87 QELVLRKNKVNGVDTWAFHNLNDLLILDLSYNLIQSLDTVDLTDLKHLQIFDLSHNRIHTIQMGT 151

  Fly   204 FGHVPQLVKLELSDCRLSHIAVRAFAGLESSLE---WLKLDGNRLSEVRS-GTITSLASLHGLEL 264
            .|.:..|.:|:||...:|..  |:.|...|.|.   .|.|..|.:::::| .::|.|:||..|.|
 Frog   152 LGPLGALQELDLSFNNVSDF--RSVANAVSQLPDFLRLSLSSNFITDLKSEQSVTVLSSLQSLNL 214

  Fly   265 ARNT 268
            ..|:
 Frog   215 RNNS 218

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek3NP_001162986.1 LRR_RI <110..267 CDD:238064 48/160 (30%)
leucine-rich repeat 112..137 CDD:275380 9/24 (38%)
LRR_8 137..196 CDD:290566 18/58 (31%)
leucine-rich repeat 138..161 CDD:275380 6/22 (27%)
leucine-rich repeat 162..185 CDD:275380 8/22 (36%)
LRR_8 184..245 CDD:290566 18/63 (29%)
leucine-rich repeat 186..209 CDD:275380 6/22 (27%)
leucine-rich repeat 210..234 CDD:275380 7/23 (30%)
leucine-rich repeat 235..258 CDD:275380 7/26 (27%)
LRRCT 267..316 CDD:214507 1/2 (50%)
IG_like 328..428 CDD:214653
Ig 335..425 CDD:143165
tlr13XP_002935047.2 LRR_RI <29..220 CDD:238064 54/194 (28%)
leucine-rich repeat 62..85 CDD:275380 9/24 (38%)
LRR_8 63..144 CDD:290566 26/82 (32%)
leucine-rich repeat 86..133 CDD:275380 14/46 (30%)
LRR_8 132..192 CDD:290566 17/61 (28%)
leucine-rich repeat 134..157 CDD:275380 6/22 (27%)
leucine-rich repeat 158..208 CDD:275380 15/51 (29%)
LRR_8 186..242 CDD:290566 11/33 (33%)
leucine-rich repeat 209..231 CDD:275380 4/10 (40%)
leucine-rich repeat 232..307 CDD:275380
LRR_RI 253..534 CDD:238064
leucine-rich repeat 308..331 CDD:275380
leucine-rich repeat 332..355 CDD:275380
leucine-rich repeat 356..379 CDD:275380
LRR_8 379..438 CDD:290566
leucine-rich repeat 380..403 CDD:275380
leucine-rich repeat 404..427 CDD:275380
leucine-rich repeat 428..451 CDD:275380
leucine-rich repeat 452..475 CDD:275380
LRR_8 474..534 CDD:290566
leucine-rich repeat 476..499 CDD:275380
LRR_8 499..587 CDD:290566
leucine-rich repeat 500..523 CDD:275380
leucine-rich repeat 524..577 CDD:275380
leucine-rich repeat 578..631 CDD:275380
LRR_8 631..685 CDD:290566
leucine-rich repeat 632..655 CDD:275380
leucine-rich repeat 656..676 CDD:275380
TIR 792..935 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.