DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lace and SPT1

DIOPT Version :9

Sequence 1:	NP_001285957.1	Gene:	lace / 34910	FlyBaseID:	FBgn0002524	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001325849.1	Gene:	SPT1 / 824039	AraportID:	AT3G48780	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	471	Identity:	213/471 - (45%)
Similarity:	299/471 - (63%)	Gaps:	6/471 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 VPLHTACLTYLGFYLLMILGYI---NQLLFVPKVATEKGRDGYVALYDAFESFYSRYVYRRIKDC 179
            :|..||..||..:.||...|.:   ::|:|  .........||..:..|.|.||.|.:|.||:||
plant     4 IPYLTAVSTYFSYGLLFAFGQLRDYSRLIF--DWWRTNNLQGYAPICLAHEDFYIRRLYHRIQDC 66

  Fly   180 WNRPICSVPGDELTLKDRVTDDYGWSFKFTGTETRCLNLGSYNYLGFAAATGQCADDSEESARSS 244
            :.|||.|.|...:.:.:||:||...:.|.|...:|||||||||||||.:....|.....||.:..
plant    67 FGRPISSAPDAWIDVVERVSDDNNKTLKRTTKTSRCLNLGSYNYLGFGSFDEYCTPRVIESLKKF 131

  Fly   245 GLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHA 309
            ..:.||||.:.|......|||...|:|.|...|::||||:|||:..:|.|:|...|:|||..||.
plant   132 SASTCSSRVDAGTTSVHAELEDCVAKYVGQPAAVIFGMGYATNSAIIPVLIGKGGLIISDSLNHT 196

  Fly   310 SIILGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLP 374
            ||:.|.|.||||.:||:||....||:||::.:..|.|:. .:||.|::::||||:||||.|..||
plant   197 SIVNGARGSGATIRVFQHNTPGHLEKVLKEQIAEGQPRT-HRPWKKIIVVVEGIYSMEGEICHLP 260

  Fly   375 EVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKK 439
            |::::.||||||:|||||||:||:|..||||.:...||..:|||:||||||||||.|||:||||.
plant   261 EIVSICKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTSDVDIMMGTFTKSFGSCGGYIAGSKD 325

  Fly   440 LIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGV 504
            ||.:|:....||.||.|||.|.|.||::::|.|:||||::.|.:|:.::..|:.:||..|.::|.
plant   326 LIQYLKHQCPAHLYATSISTPSATQIISAIKVILGEDGSNRGAQKLARIRENSNFFRAELQKMGF 390

  Fly   505 ITYGHEDSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDF 569
            ...|..||||:|:::|..:||.|..|.....::|.|..||||||::..|.|.|:||:|::|.|..
plant   391 EVLGDNDSPVMPIMLYNPAKIPAFSRECLRENLAVVVVGFPATPLLLARARICISASHSREDLIK 455

  Fly   570 ALEAIDEIADDLGLKY 585
            ||:.|.:..|..|:||
plant   456 ALQVISKAGDLTGIKY 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_001285957.1	PLN02483	117..587	CDD:178101	213/471 (45%)
lace	NP_001285957.1	BioF	164..577	CDD:223234	196/412 (48%)
SPT1	NP_001325849.1	PLN02483	1..489	CDD:178101	213/471 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	356	1.000	Domainoid score	I202
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21610
Inparanoid	1	1.050	411	1.000	Inparanoid score	I453
OMA	1	1.010	-	-		QHG53569
OrthoDB	1	1.010	-	-		D438936at2759
OrthoFinder	1	1.000	-	-		FOG0001517
OrthoInspector	1	1.000	-	-		otm3235
orthoMCL	1	0.900	-	-		OOG6_100700
Panther	1	1.100	-	-	LDO	PTHR13693
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X956
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840