Protein Alignment lace and alas2

DIOPT Version :9

• Sequence 1: NP_001285957.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_571757.1
• Gene: alas2 / 64607
• ZFINID: ZDB-GENE-001229-1
• Length: 583
• Species: Danio rerio
• Alignment Length: 454
• Identity: 122/454 - (26%)
• Similarity: 203/454 - (44%)
• Gaps: 54/454 - (11%)

  Fly   159 ALYDAFESFYSRYVYRRIKDCWNRPICSVPGDEL-------TLKD------RVTDDYGWSFKFTG 210
            :|:...:|..|......::|.:|||..|.  ||.       ..||      :..:.:...|.|..
Zfish   112 SLFSGLQSHQSTGPTHLLQDNFNRPTFSY--DEFFTQKIVEKKKDHTYRIFKTVNRFAEVFPFAE 174

  Fly   211 TETRCLNLGSY-------NYLGFA------AATGQCADDSEESARSSGLAYCSSRCELGDNEQLQ 262
            ..:....|||.       :|||.:      .|.|       ::.:..|.....:|...|.:....
Zfish   175 DYSIAGRLGSQVSVWCSNDYLGMSRHPRVVKAIG-------DALKKHGAGAGGTRNISGTSNYHV 232

  Fly   263 ELEALTARYFGVEDAIVFGMGFATNALNLPSL--LGPNSLVISDEKNHASIILGLRLSGATTKVF 325
            .||...||....:.|:||...|..|...|.:|  :.|...:.||..||||:|.|:|.|||...:|
Zfish   233 ALENELARLHQKDGALVFSSCFVANDSTLFTLAKMLPGCEIYSDMGNHASMIQGIRNSGAKRFIF 297

  Fly   326 KHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLD 390
            :||:...||.:|.:          ..|....::..|.:.||:|:|..|.|:..:..||.|..::|
Zfish   298 RHNDASHLEELLSR----------SDPLTPKIVAFETVHSMDGAICPLEELCDVAHKYGALTFVD 352

  Fly   391 EAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAA 455
            |.|:||..|:.|.||.:..||..| :||:.||..|:||..|||:|.:..|:|.:|:.:....:..
Zfish   353 EVHAVGLYGAHGAGVGERDNVMHK-IDIVSGTLGKAFGCVGGYIASTAALVDTVRSFAAGFIFTT 416

  Fly   456 SISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHEDSPVVPMLVY 520
            |:.|.:....|.|::.:..::|..:  ::.||  ||.::.|:.|...| :...:..|.::|:.|.
Zfish   417 SLPPMVLAGALESVRVLKSDEGQAL--RRAHQ--RNVKHMRQLLLDAG-LPVVNCPSHIIPIRVG 476

  Fly   521 LFSKIGAVVRTLTTRHIAAVGA-GFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDEIADDLGL 583
            ..:|...|...|..:|...|.| .:|..|..|..:|...|..|....:::..|.:.::..::||
Zfish   477 NAAKNSEVCDILLEKHNIYVQAINYPTVPRGEELLRLAPSPFHNPIMMNYFAEKLLDVWQEVGL 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_001285957.1	PLN02483	117..587	CDD:178101	122/454 (27%)
		BioF	164..577	CDD:223234	119/441 (27%)
alas2	NP_571757.1	Preseq_ALAS	3..98	CDD:286162
		AAT_I	138..542	CDD:302748	115/428 (27%)
		BioF	138..535	CDD:223234	113/421 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810