Protein Alignment lace and alas1

DIOPT Version :10

• Sequence 1: NP_476614.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001008072.1
• Gene: alas1 / 493434
• XenbaseID: XB-GENE-975179
• Length: 628
• Species: Xenopus tropicalis
• Alignment Length: 571
• Identity: 138/571 - (24%)
• Similarity: 234/571 - (40%)
• Gaps: 98/571 - (17%)

  Fly    38 EKQELLRKFSAPAYTEIRTRRCQPKPANDAQSPSSINYHPEKKSIPNGHASILD--QESKPNQAE 100
            |...::||.|.....:::..:...|   |.:.|.:......|.::.. :.|:|:  |||..:|..
 Frog   107 ENSSVIRKASPETQEDVQKMQTMRK---DLRGPITKGAGEAKMTLQK-NRSVLEKFQESVLHQRP 167

  Fly   101 GKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILGYINQLLFVPKVATEKGRDGYVALYDAFE 165
            ..:|..|:       :.:|.......|..|:              .|...||..|
 Frog   168 AVVSHLLQ-------DNMPKAVKTFKYDKFF--------------EKKIDEKKND---------- 201

  Fly   166 SFYSRYVYRRIKDCWNR----PICSVPGDELTLKDRVTDDYGWSFKFTGTETRCLNLGSYNYLGF 226
                 :.||..|....|    |:.....|.|..|..|:   .|          |.|    :|||.
 Frog   202 -----HTYRVFKTVNRRAEVFPMADDYSDTLISKKTVS---VW----------CSN----DYLGM 244

  Fly   227 A---AATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNA 288
            :   ...|...:..::....:|    .:|...|.::...|||...|...|.:.|::|...|..|.
 Frog   245 SRHPKVVGAVMETLKQHGAGAG----GTRNISGTSKFHVELEHELADLHGKDAALLFSSCFVAND 305

  Fly   289 LNLPSL--LGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQ 351
            ..|.:|  :.|...:.||..||||:|.|:|.|.|...||:||::..|..:|          |...
 Frog   306 STLFTLAKMLPGCEIYSDAGNHASMIQGIRNSRAPKYVFRHNDVGHLRELL----------KNSD 360

  Fly   352 PWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEV 416
            |....::..|.:.||:|::..|.|:..:..:|.|..::||.|:||..|:||.|:.|...|..| :
 Frog   361 PSTPKIVAFETVHSMDGAVCPLEEMCDVSHEYGAITFVDEVHAVGLYGARGGGIGDRDGVMTK-M 424

  Fly   417 DILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIG 481
            ||:.||..|:||..|||:|.:..|||.:|:.:....:..|:.|.:....:.|::.:..|:|..:.
 Frog   425 DIISGTLGKAFGCVGGYIASTSALIDTVRSYAAGFIFTTSLPPMLLSGAIASVRVLKSEEGQALR 489

  Fly   482 RKKIHQLARNTRYFRRRLAQLGVITYGHEDSPVVPMLVYLFSKIGAVV-RTLTTRHIAAVGAGFP 545
            |:  ||  ||.:..|:.|...| :...|..|.::|:.|...:|...:. :.:...:|......:|
 Frog   490 RQ--HQ--RNVKLMRQMLMDSG-LPVVHCPSHIIPIRVSDAAKNTEICDKLMRDYNIYVQAINYP 549

  Fly   546 ATPIMEGRIRFCLSAAHTKEQLDFALEAIDEI--ADDLGLKYSRKPRDPNP 594
            .....|..:|...:..|..:.:.:.|:.:...  :.||.||       |:|
 Frog   550 TVARGEELLRIAPTPHHNPQMMSYFLDKLLTTWKSVDLELK-------PHP 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_476614.1	AAT_I	117..587	CDD:450240	120/481 (25%)
alas1	NP_001008072.1	Preseq_ALAS	2..127	CDD:462658	4/19 (21%)
		AAT_I	185..590	CDD:450240	117/470 (25%)