Protein Alignment lace and Sptlc3

DIOPT Version :10

• Sequence 1: NP_476614.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001099987.1
• Gene: Sptlc3 / 296188
• RGDID: 1310030
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 233/545 - (42%)
• Similarity: 355/545 - (65%)
• Gaps: 27/545 - (4%)

  Fly    76 HPEKKSIPNGHASILDQESKPNQAEGK------LSPELEHFQKTS---------FEEVPLHTACL 125
            :|...::.||  ::.:.:::|.:.:..      :|.|.:..:|..         :.|.||:....
  Rat     3 NPRDSAVTNG--TLRNPKTQPGKRQSTDCVKNGISKEAQQNRKAEEDDKLVFKPYPEPPLYVFVF 65

  Fly   126 TYLGFYLLMILGYINQLL---FVPK----VATEKGRDGYVALYDAFESFYSRYVYRRIKDCWNRP 183
            ||:|:.:.|:.||:...:   .:.|    |..|:.:| :|.||..||:||:|.:|.||:|.|:..
  Rat    66 TYMGYGIGMLFGYLRDFMRNWGIEKCNAAVEREEQKD-FVPLYQDFENFYTRNLYMRIRDSWSHT 129

  Fly   184 ICSVPGDELTLKDRVTDDYGWSFKFTGTETR-CLNLGSYNYLGFAAATGQCADDSEESARSSGLA 247
            :||||.....:.::|||||.|:|:.||...: .:|:.||||||.|:...:..:..:::....|:.
  Rat   130 VCSVPVPNFDIMEKVTDDYNWTFRHTGKVIKNVINMASYNYLGLASKYNESMEKVKDTIEKYGVG 194

  Fly   248 YCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASII 312
            ..|:|.|:|..:...|||.|.|::..||..:|||||||||:.|:|..:|...|::|||.||.|:|
  Rat   195 VASTRNEMGSLDIHNELEDLMAKFLNVEAVMVFGMGFATNSTNIPIFVGKGCLILSDEFNHTSVI 259

  Fly   313 LGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVI 377
            ||.|||||..:.|||||:::||::||:.:..|.|:. |:.|.|::|||||::|||||||.||:::
  Rat   260 LGSRLSGAVIRPFKHNNIQNLEKLLREAIIRGQPRT-GRAWKKILILVEGVYSMEGSIVNLPQIV 323

  Fly   378 ALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLID 442
            |||||||||||:|||||:|..|:.|:|:.:.|.:.|:::||.||||||||.::|||:||.|:::|
  Rat   324 ALKKKYKAYLYMDEAHSIGCTGTMGQGIRELFGLAPEDIDIYMGTFTKSFAASGGYIAGKKEIVD 388

  Fly   443 FLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITY 507
            ::|..||:..||.|:||.:|.||:.|:|.:||.:|...|.::|.||..|.:||||||.::|.|.|
  Rat   389 YVRVQSHSATYATSMSPVVAAQIIRSLKIMMGYEGNFGGVQRIQQLRENIKYFRRRLIEMGFIIY 453

  Fly   508 GHEDSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALE 572
            |::.|||||:|:|:.:|:.|..|.|..:.||.|..|||||.:.|||.||.||:|||:|.||..||
  Rat   454 GNDYSPVVPVLLYMPAKVSAFGRLLLKKKIAVVVVGFPATSLPEGRARFSLSSAHTREMLDTVLE 518

  Fly   573 AIDEIADDLGLKYSRKPRDPNPVIY 597
            .:|:|.|.|.:||....:....|:|
  Rat   519 VVDKIGDLLNVKYFPYKKSGRAVLY 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_476614.1	AAT_I	117..587	CDD:450240	224/477 (47%)
Sptlc3	NP_001099987.1	AAT_I	59..533	CDD:450240	223/475 (47%)