Protein Alignment lace and sptl-2

DIOPT Version :10

• Sequence 1: NP_476614.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_505064.1
• Gene: sptl-2 / 266646
• WormBaseID: WBGene00018398
• Length: 586
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 255/513 - (49%)
• Similarity: 346/513 - (67%)
• Gaps: 23/513 - (4%)

  Fly    90 LDQESKPNQAE-------GKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILGYINQLL---- 143
            :||.|:...:.       ||.:|       ..||::...|....|:.:..|.:..:|.:.:
 Worm    72 VDQGSEETTSSHDIYGDVGKRAP-------NEFEKIDRLTTIKVYIAWLALFVFAHIREYVTRFG 129

  Fly   144 FVPKVATE---KGRDGYVALYDAFESFYSRYVYRRIKDCWNRPICSVPGDELTLKDRVTDDYGWS 205
            ||..::::   |.:| :|.|:..||:||.|..|.:::|.:.||||||||..:.|.|||:.|..|:
 Worm   130 FVKDLSSKENAKMKD-FVPLFSDFEAFYQRNCYIKVRDVFERPICSVPGATVDLVDRVSHDGNWT 193

  Fly   206 FKFTGTETRCLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTAR 270
            :::.||.|..:|:|||||||||.:.|.||:.|..|....||:.|::..|.|.:....:||.|.|.
 Worm   194 YEYPGTRTNVINVGSYNYLGFAQSAGPCAEQSASSIDREGLSCCTTVHERGRSVSQAKLEKLVAE 258

  Fly   271 YFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLER 335
            :.||||||.|.||||||::|.|.|:..:||:|||:.||||:|||.|||||:||||:||:|..|||
 Worm   259 FLGVEDAICFSMGFATNSMNAPCLVDKHSLIISDKYNHASLILGCRLSGASTKVFEHNDMESLER 323

  Fly   336 VLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGS 400
            :||..:.|||||. .:|:.|::|:||||:||||||..||.:|||||||:||||||||||:||||.
 Worm   324 ILRDAIAYGNPKT-HRPYKKILIIVEGIYSMEGSICNLPGIIALKKKYQAYLYLDEAHSIGAMGK 387

  Fly   401 RGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQI 465
            .|:||.:|:..|||:|||||||||||||:||||:||||:.:|.||..|....|::.:||||||||
 Worm   388 TGKGVVEYWGCDPKDVDILMGTFTKSFGAAGGYIAGSKRTVDHLRAASPTGYYSSPMSPPIAQQI 452

  Fly   466 LTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHEDSPVVPMLVYLFSKIGAVVR 530
            .|||..|||:|||..|.::|.:||||:.|||.:|.|.|.|.||..||||||||:|..:..|...|
 Worm   453 YTSMSIIMGKDGTKDGAQRIERLARNSHYFRMKLKQNGFIVYGSNDSPVVPMLIYFPTMCGFYGR 517

  Fly   531 TLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDEIADDLGLKYSRK 588
            .:..|:|..|...||||.:.|||:|||:||||||||||..||.::.:......|:|::
 Worm   518 EMLARNIGCVVVSFPATHMTEGRVRFCISAAHTKEQLDEVLETVNLLGSMSRSKFSKR 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_476614.1	AAT_I	117..587	CDD:450240	246/476 (52%)
sptl-2	NP_505064.1	AAT_I	103..585	CDD:450240	247/475 (52%)