Protein Alignment lace and hem1

DIOPT Version :10

• Sequence 1: NP_476614.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_594388.1
• Gene: hem1 / 2542028
• PomBaseID: SPAC2F3.09
• Length: 558
• Species: Schizosaccharomyces pombe
• Alignment Length: 585
• Identity: 142/585 - (24%)
• Similarity: 230/585 - (39%)
• Gaps: 138/585 - (23%)

  Fly    32 ADLSAPEKQELLRKFSAPAYTEIR---------TRRCQ----PKPANDAQSPSSINYHPEKKSIP 83
            ||:|...|.:..:....|:..||.         :|.|:    .|.|.:|.:.:.:.   :|..:|
pombe    53 ADVSRGFKSDSKQMAMEPSLDEIHLKAGVVNTGSRTCRHADAVKAAAEAATTTPVT---KKHQMP 114

  Fly    84 NGHASILDQESKPNQAEGKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILGYINQLLFVPKV 148
            ..:||.|:...                        |..|....|..||              .:.
pombe   115 KHYASDLNGVG------------------------PATTPRFDYDTFY--------------REE 141

  Fly   149 ATEKGRDGYVALYDAFESFYSRYVYRRIKD------CWNRPICSVPGDELTLKDRVTDDYGWSFK 207
            ..:|.||.....::........|....:.|      .|    ||             :||
pombe   142 LDKKHRDKSYRYFNNINRLAKEYPLAHLADPNTRVEVW----CS-------------NDY----- 184

  Fly   208 FTGTETRCLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYF 272
                    ||:|.:..:  ..|..||.:       :.|.....:|...|.|:....||...|...
pombe   185 --------LNMGGHKKI--REAMHQCIE-------TYGGGAGGTRNIAGHNQHAVRLEKSLADLH 232

  Fly   273 GVEDAIVFGMGFATNALNLPSLLG---PNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLE 334
            ....|:|||..:..|...| |.||   ||.:.:|||.||||:|.|:|.|.....:||||::.|||
pombe   233 QKPAALVFGSCYVANDATL-STLGRKLPNCIFLSDEMNHASMINGIRNSRCEKIIFKHNDLVDLE 296

  Fly   335 RVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMG 399
            ..| ..:....||         :|..|.::||.|::..:.|:..|.|||.|..:|||.|:||..|
pombe   297 AKL-ASLPLNRPK---------IIAFESVYSMSGNVAPISEICDLAKKYGAITFLDEVHAVGMYG 351

  Fly   400 SRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQ 464
            .||.||.:........|||:.||..||:|..|||:|.|..|:|.:|:.:....:..|:.|.:...
pombe   352 PRGAGVAEETPGLLSRVDIITGTLAKSYGCVGGYIAASSTLVDMIRSLAPGFIFTTSLPPHVMVG 416

  Fly   465 ILTSMKTIMGEDGTDIGRKKIHQLARN-----TRYFRRRLAQLGVITYGHEDSPVVPMLV---YL 521
            .||:::.:           |:..:.|.     .|..::.|:::|:....: |:.:||.:|   :|
pombe   417 ALTAVEHL-----------KVSNVEREQQRSAVRRVKQSLSEIGIPVLSN-DTHIVPAMVGDAHL 469

  Fly   522 FSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDEIADDLGLKYS 586
             :|: |....|...:|......||...:...|:|...:.||..|..   ::::....:|:..|::
pombe   470 -AKL-ASDSLLHDHNIYVQSINFPTVSVGTERLRITPTPAHNTEHY---VQSLTNAMNDVWSKFN 529

  Fly   587  586
            pombe   530  529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_476614.1	AAT_I	117..587	CDD:450240	125/487 (26%)
hem1	NP_594388.1	AAT_I	132..532	CDD:450240	123/479 (26%)