Protein Alignment lace and Sptlc3

DIOPT Version :10

• Sequence 1: NP_476614.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_780676.1
• Gene: Sptlc3 / 228677
• MGIID: 2444678
• Length: 563
• Species: Mus musculus
• Alignment Length: 556
• Identity: 236/556 - (42%)
• Similarity: 351/556 - (63%)
• Gaps: 40/556 - (7%)

  Fly    65 NDAQSPSSINYHPEKKS--------IPNGHASILDQESKPNQ---AEGKLSPELEHFQKTSFEEV 118
            ||:...:...::|:.:.        :.||    :.:|::.|:   ||.|  |..|.:|     |.
Mouse     5 NDSAVTNGTLHNPKTQQGKRQSTGCVKNG----ISKEAQQNRKAYAEDK--PVFEPYQ-----EA 58

  Fly   119 PLHTACLTYLGFYLLMILGYINQLL---FVPK----VATEKGRDGYVALYDAFESFYSRYVYRRI 176
            ||:...|||:|:.:.::.||:...:   .:.|    |..|:.:| :|.||..||:||.|.:|.||
Mouse    59 PLYVYVLTYMGYGIGILFGYLRDFMRNWGIEKCNAAVEREEQKD-FVPLYQDFENFYKRNLYMRI 122

  Fly   177 KDCWNRPICSVPGDELTLKDRVTDDYGWSFKFTG-TETRCLNLGSYNYLGFAAATGQCADDS--- 237
            :|.|:..:||.|...:.:.::|||||.|:|:.|| .....:|:.||||||.|..    .|||
Mouse   123 RDSWSHTVCSAPEPYMNVMEKVTDDYNWTFRHTGKVIENIINMASYNYLGLAGK----YDDSMVR 183

  Fly   238 -EESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLV 301
             :::....|:...|:|.|:|..:..:|||.|.|.:..||..:.|||||||||:|:|..:|...|:
Mouse   184 VKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLI 248

  Fly   302 ISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSM 366
            :|||.||.|:|||.|||||..:.|||||..:||::||:.:..|.|.. |:.|.|::|:|||::||
Mouse   249 LSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRGQPGT-GRAWKKILIVVEGVYSM 312

  Fly   367 EGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAG 431
            |||||.|.:::|||||||||||:|||||:|..|..||||.:.|.:||:::|:.||||||||..:|
Mouse   313 EGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSG 377

  Fly   432 GYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFR 496
            ||:.|.|:::|:||..||:..||.|:||.:|.|::.|:|..||.:|...|.::|.||..|.:|||
Mouse   378 GYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFR 442

  Fly   497 RRLAQLGVITYGHEDSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAA 561
            |||.::|.|.||::.|||:|:|:|:.:|:.|..|.|..:.|:.|..|||||.:.|||.||.:|:|
Mouse   443 RRLKEMGFIIYGNDFSPVIPVLLYMPAKVSAFSRFLLKKKISVVVVGFPATSLPEGRARFSMSSA 507

  Fly   562 HTKEQLDFALEAIDEIADDLGLKYSRKPRDPNPVIY 597
            ||:|.||..||.:||:.|.|.:||....:....::|
Mouse   508 HTREMLDTVLEVVDELGDLLNVKYFPLKKSGRAILY 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_476614.1	AAT_I	117..587	CDD:450240	222/481 (46%)
Sptlc3	NP_780676.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		3/26 (12%)
		AAT_I	56..535	CDD:450240	223/489 (46%)