Protein Alignment lace and sptl-3

DIOPT Version :10

• Sequence 1: NP_476614.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001256547.1
• Gene: sptl-3 / 179884
• WormBaseID: WBGene00011932
• Length: 521
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 241/597 - (40%)
• Similarity: 342/597 - (57%)
• Gaps: 104/597 - (17%)

  Fly    11 VFEQSYATTNG----NGKVPNGNGAADLSAPEKQELLRKFSAPAYTE--IRTRRCQPKPANDAQS 69
            ||.....|.||    |||..|||                     .||  |:...| ||||
 Worm     6 VFYNMGGTQNGKAVANGKAKNGN---------------------ITEKVIKLDPC-PKPA----- 43

  Fly    70 PSSINYHPEKKSIPNGHASILDQESKPNQAEGKLSPELEHFQKTSFEEVPLHTACLTYLGFYL-- 132
                                                                     :..|:|
 Worm    44 ---------------------------------------------------------FYVFWLVQ 51

  Fly   133 ----LMILGYINQLLF----VPKVATEKG---RDGYVALYDAFESFYSRYVYRRIKDCWNRPICS 186
                :|::|.:...||    :.|....||   .:.:..|.::|::.|:.::||:..|..||||..
 Worm    52 LNITMMLVGAMVATLFDKWGIVKTKRSKGDPRMESFQPLGNSFDATYTDHIYRQSTDVVNRPISG 116

  Fly   187 VPGDELTLKDRVTDDYGWSFKFTGTETRCLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSS 251
            |||..:.||||.|||:||:.|:||||:..:||||||||||:..:|.||:.:.......|:....|
 Worm   117 VPGAIVRLKDRYTDDHGWTQKYTGTESEVINLGSYNYLGFSHRSGVCAEAAAAHIDKYGINCGGS 181

  Fly   252 RCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLR 316
            |.|:|::...:.:|:..|:|..|||||||.||||||::|:|||:...||::||..||||::.|.|
 Worm   182 RQEIGNHVAHKSVESTIAQYLNVEDAIVFPMGFATNSMNIPSLVDKGSLILSDRLNHASLVTGCR 246

  Fly   317 LSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKK 381
            ||||.|.||:||:..|.||.||..:|..:||. |:.::||:|::|||:||||:||.||..||:||
 Worm   247 LSGAHTVVFRHNDASDCERKLRDALCGVSPKT-GEKYNKVLIIIEGIYSMEGTIVNLPAFIAVKK 310

  Fly   382 KYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRT 446
            ||..||:||||||:||:|..||||.:|:..:|:::||:|||.||||.|||||:.||||:||.:|.
 Worm   311 KYNCYLFLDEAHSIGAVGPSGRGVAEYWGCNPRDIDIMMGTLTKSFASAGGYMGGSKKVIDHIRR 375

  Fly   447 NSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHED 511
            .|...||..::|||:..|:..::..:.|:|||||||:|..||..|:||||:.|.:.|.:.||:.|
 Worm   376 YSAGTCYGVTMSPPLIAQVERAVLIMSGKDGTDIGRQKAIQLLENSRYFRKELRKRGFLVYGNND 440

  Fly   512 SPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDE 576
            |||||::.:..:|:....|.:...:|..|..|:||||::|.|:||||||.||||.||:.|||:::
 Worm   441 SPVVPLMTFYITKVVEFSRRMLKHNIGIVAVGYPATPLLEARVRFCLSADHTKEHLDYILEAVEQ 505

  Fly   577 IADDLGLKYSRK 588
            :..:.|..|..|
 Worm   506 VGMETGTFYGTK 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_476614.1	AAT_I	117..587	CDD:450240	221/482 (46%)
sptl-3	NP_001256547.1	AAT_I	87..514	CDD:450240	211/427 (49%)