Protein Alignment lace and Alas

DIOPT Version :10

• Sequence 1: NP_476614.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_061497049.1
• Gene: Alas / 1273856
• VectorBaseID: AGAMI1_012604
• Length: 596
• Species: Anopheles gambiae
• Alignment Length: 618
• Identity: 149/618 - (24%)
• Similarity: 233/618 - (37%)
• Gaps: 150/618 - (24%)

  Fly    11 VFEQSYATTNGNGKVPNGNGAADLSAPEKQELLRKFSAPAYTEIR---TRRCQPKPANDAQSPSS 72
            |.:::.:|..|.  .|...||....|.|......|  ..|.||.|   :...||.|..  |.|::
Mosquito    54 VVQRTISTLQGG--APAAGGAVGSGAQETPTTTVK--KDASTEARRNLSSMQQPHPVQ--QQPAA 112

  Fly    73 INYHPEKKSIPNGHASILDQESKPNQAEGKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILG 137
            .|..|                        .||....|.:|...|.|.
Mosquito   113 GNKCP------------------------FLSTAAPHVKKLGAESVE------------------ 135

  Fly   138 YINQLLFVPKVATEKGRDGYVALYDAFESFYSRYVYRRIKDCWNRPICSVPGDELTLKDRVTDD- 201
                   :|...|.:           :|.|:...:.|:.:|...|....|        :|:..|
Mosquito   136 -------IPAERTFQ-----------YEDFFHEQILRKKQDHSYRVFKKV--------NRLAADG 174

  Fly   202 -------YGWSFKFTGTETRCLNLGSYNYLGFAA---ATGQCADDSEESARSSGLAYCSSRCELG 256
                   |.|..:  .....|.|    :|||.:.   .....||..|.....:|    .:|...|
Mosquito   175 QFPRALEYSWGER--PITVWCSN----DYLGMSCHPEVKRAVADALETYGTGAG----GTRNISG 229

  Fly   257 DNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLG--PNSLVISDEKNHASIILGLRLSG 319
            ::...:.||...|.....|.|::|...|..|...|.:|..  |...:.||..||||:|.|:|.||
Mosquito   230 NSMNHENLERRLAELHQKESALLFTSCFVANDSTLFTLAKALPGCHIFSDAGNHASMIQGIRNSG 294

  Fly   320 ATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYK 384
            ....:|:||:...| |.|.|.|....||         ::..|.:.||.|::..|.|:..:..:|.
Mosquito   295 VPKHIFRHNDPAHL-RELLQRVDRSLPK---------IVAFETVHSMSGAVCPLEELCEIAHEYG 349

  Fly   385 AYLYLDEAHSVGAMGSRGRGVTDYFNVDPKE-----VDILMGTFTKSFGSAGGYLAGSKKLIDFL 444
            |..::||.|:||..|..|.|:.:      :|     :||:.||..|:||:.|||:||:..|||.:
Mosquito   350 ALTFVDEVHAVGLYGEHGAGIGE------REGQLHNMDIISGTLGKAFGNVGGYIAGTALLIDMI 408

  Fly   445 RTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGH 509
            |:.:....:..|:.|.:....|.::..:..|:|.::..:  ||  .|.||.|:||.:.| ....|
Mosquito   409 RSYAAGFIFTTSLPPTVLCGALKAVDILASEEGRELRAR--HQ--SNVRYLRKRLQEEG-FPVEH 468

  Fly   510 EDSPVVPMLVYLFSKIG--AVVRTLTTRHIAAVG-----AGFPATPIMEGRIRFCLSAAHTKEQL 567
            ..|.::|:      |||  .....|:.|.|...|     ..:|.....|.::|...:..||:..:
Mosquito   469 TPSHIIPV------KIGNPQQCTELSDRMIQRFGHYVQAINYPTVARGEEKLRLAPTPHHTRAMM 527

  Fly   568 DFALEAIDEIADDLGL-----------KYSRKP 589
            |..:..:..:..||.:           .:.|||
Mosquito   528 DELVRDMKVVWQDLKMPLGGKHCPEECAFCRKP 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_476614.1	AAT_I	117..587	CDD:450240	121/505 (24%)
Alas	XP_061497049.1	None