Protein Alignment lace and SPTLC1

DIOPT Version :9

• Sequence 1: NP_001285957.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001268232.1
• Gene: SPTLC1 / 10558
• HGNCID: 11277
• Length: 513
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 87/271 - (32%)
• Similarity: 145/271 - (53%)
• Gaps: 20/271 - (7%)

  Fly   215 CLNLGSYNYLGF-------AAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYF 272
            |:|..|:|:||.       |||..        |.:..|:..|..|...|..:...:||...|::.
Human   100 CINFASFNFLGLLDNPRVKAAALA--------SLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFM 156

  Fly   273 GVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVL 337
            ..|:||::..||||.|..:|:......:|..|.....:|..||:.|.:..|:||||:|.||||:|
Human   157 KTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLL 221

  Fly   338 RQGVC--YGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGS 400
            ::...  ..||:|...  .:..|:|||::...|:|..|||::.||.||||.::|:|:.|.|.:|.
Human   222 KEQEIEDQKNPRKARV--TRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGE 284

  Fly   401 RGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQI 465
            .|||||:::.::..::|::......:..|.||:..|...:||..|.:...:|::||:.|.:|...
Human   285 HGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAA 349

  Fly   466 LTSMKTIMGED 476
            :.:: .||.|:
Human   350 IEAL-NIMEEN 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_001285957.1	PLN02483	117..587	CDD:178101	87/271 (32%)
		BioF	164..577	CDD:223234	87/271 (32%)
SPTLC1	NP_001268232.1	AAT_I	11..442	CDD:418510	87/271 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312139at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820