Protein Alignment lace and sptlc2

DIOPT Version :10

• Sequence 1: NP_476614.1
• Gene: lace / 34910
• FlyBaseID: FBgn0002524
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_002938915.2
• Gene: sptlc2 / 100380000
• XenbaseID: XB-GENE-946143
• Length: 553
• Species: Xenopus tropicalis
• Alignment Length: 532
• Identity: 289/532 - (54%)
• Similarity: 382/532 - (71%)
• Gaps: 25/532 - (4%)

  Fly    71 SSINYHPEKKSIPNGHASILDQESKPNQAEGKLSPELEH--------FQKTSFEEVPLHTACLTY 127
            |.:|:.|....:.......|        ..|.:|.|..|        |.: :|||.|:..|.|||
 Frog    11 SGLNHKPVMNGVQRWENGAL--------KNGMMSEEKVHNGGLYKRPFNE-AFEETPMLVAVLTY 66

  Fly   128 LGFYLLMILGYINQLLFVPK-----VATEK-GRDGYVALYDAFESFYSRYVYRRIKDCWNRPICS 186
            :|:.:|.:.||:...|...|     :|||: .:..:|.||..||:||:|.:|.||:|.||||:||
 Frog    67 MGYGILTLFGYLRDFLRTWKIEKCHIATERVEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPVCS 131

  Fly   187 VPGDELTLKDRVTDDYGWSFKFTGTETR-CLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCS 250
            |||:.:.:.:|.||||.|:|||||...: .:|:|||||||||..||.|||.|.:|....|...||
 Frog   132 VPGERIDVMERFTDDYNWTFKFTGRVIKGVINMGSYNYLGFAQNTGFCADASAKSLNQYGAGMCS 196

  Fly   251 SRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGL 315
            :|.|:|:.|:.:|||.|.||:.|||.|:.:|||||||::|:|:|:|...|::|||.||:|::||.
 Frog   197 TRQEIGNMEKHEELEHLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHSSLVLGA 261

  Fly   316 RLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALK 380
            ||||||.::||||||:.||::||..:..|.|:. .:||.|::|:||||:||||||||||||||||
 Frog   262 RLSGATIRIFKHNNMQSLEKLLRDAIVQGQPRT-HRPWKKILIVVEGIYSMEGSIVRLPEVIALK 325

  Fly   381 KKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLR 445
            ||||||||||||||:||:|..||||.|||.:||::|||:||||||||||||||:.|||.||::||
 Frog   326 KKYKAYLYLDEAHSIGALGPNGRGVVDYFGLDPRDVDIMMGTFTKSFGSAGGYIGGSKVLIEYLR 390

  Fly   446 TNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHE 510
            .:||:..||.|:|.|:.|||::|||.|||||||.:|:|::.|||.|||||||||.::|.|.||:.
 Frog   391 AHSHSAAYATSMSLPVVQQIISSMKCIMGEDGTTLGQKRVEQLAENTRYFRRRLTEMGFIIYGNS 455

  Fly   511 DSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAID 575
            ||||||:::|:.:||||..|.:..|:|..|..|||||||:|.|.|||:|||||||.||.||..|:
 Frog   456 DSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSAAHTKEMLDAALREIN 520

  Fly   576 EIADDLGLKYSR 587
            |:.|.|.|||||
 Frog   521 EVGDLLQLKYSR 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lace	NP_476614.1	AAT_I	117..587	CDD:450240	276/476 (58%)
sptlc2	XP_002938915.2	AAT_I	58..536	CDD:450240	277/476 (58%)