DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and YPR015C

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_015340.1	Gene:	YPR015C / 856125	SGDID:	S000006219	Length:	247	Species:	Saccharomyces cerevisiae

Alignment Length:	298	Identity:	74/298 - (24%)
Similarity:	111/298 - (37%)	Gaps:	75/298 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 TPERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSAFVMAAGCNPI 137
            :|.:.|||:..........|..:....|:|                  :.|..|  :|.|...|
Yeast    13 SPMKCSSSNIGGSYAQSSKEVSNTTKREVH------------------LPPCSS--IMHAPLTP- 56

  Fly   138 SALWSSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETG--SEPEDLSVRNDIPLPAL 200
                   :.:.||.|.||...| |.|::..:.....|||.|.:.:.  :.|:        |.|..
Yeast    57 -------EINQAALPPPAYHYA-PSSLHQTEDPVWRSSPNSIIFSPVIATPQ--------PFPLT 105

  Fly   201 FHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANH--AKNYRFKCDECQKMYSTSMGLSKH 263
            |      ....|...:.|::..|||    |.|...:..|  .:|:|...:|
Yeast   106 F------VERQSCCPIYSTAASSYT----AQSVPPSMQHFQEENHRAVSNE-------------- 146

  Fly   264 RQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHT-LPCKCPICGKAFSRPWLLQGHIRT 327
             |:..|.....|...|    ...:..|.:..::..:|... |..:||||||..|||..|:.|...
Yeast   147 -QYSLPNVHIGQNPGT----LLSQTQTDLDLIQKQLRAVVKLRKQCPICGKVCSRPSTLRTHYLI 206

  Fly   328 HTGEKPFQC--PDCPRSFADRSNLRAHQQTHVDVKKYA 363
            |||:.||:|  ..|.:||..:||:..|.:||  .||.|
Yeast   207 HTGDTPFKCTWEHCNKSFNVKSNMLRHLRTH--QKKIA 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	11/19 (58%)
		zf-H2C2_2	321..344	CDD:290200	10/24 (42%)
		zf-C2H2	334..356	CDD:278523	8/23 (35%)
		C2H2 Zn finger	336..356	CDD:275368	7/21 (33%)
		zf-H2C2_2	348..373	CDD:290200	7/16 (44%)
		C2H2 Zn finger	364..380	CDD:275368	74/298 (25%)
		C2H2 Zn finger	247..267	CDD:275368	2/19 (11%)
		C2H2 Zn finger	282..302	CDD:275368	2/19 (11%)
		zf-C2H2	306..328	CDD:278523	11/21 (52%)
		COG5048	307..>356	CDD:227381	23/50 (46%)
YPR015C	NP_015340.1	COG5048	<17..247	CDD:227381	73/294 (25%)
		C2H2 Zn finger	187..207	CDD:275370	11/19 (58%)
		C2H2 Zn finger	215..237	CDD:275370	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050